Version 2.77

Term Description

Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16 in cervical specimens from women with positive HPV screening assay results. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay.To report results for HPV 18/45 use Human papilloma virus 18+45 E6+E7 mRNA [Presence] in Cervix by Probe and signal amplification method [LOINC: 75694-0].
Source: Regenstrief LOINC

Part Description

LP221166-4   Human papilloma virus 16 E6+E7 mRNA
Human papilloma virus (HPV) is a double-stranded DNA virus that includes 120 types that infect cutaneous and mucosal epithelial cells. The HPV that infect the cervix are categorized as low or high risk depending upon their carcinogenicity. High risk HPV types can lead to low-grade cervical cell abnormalities, pre-cancerous cellular abnormalities and anogenital cancer. Type 16 is a high risk HPV and is implicated in roughly 50% of cervical cancers around the world. E6/E7 genes in cervical tumors interfere with the control of cell proliferation and cell division and can be used for targeted anti-cancer therapy. PMID: 9448307 Source: Regenstrief LOINC

Fully-Specified Name

Component
Human papilloma virus 16 E6+E7 mRNA
Property
PrThr
Time
Pt
System
Cvx
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
HPV 16 E6+E7 mRNA Cvx Ql NAA+probe
Display Name
HPV 16 E6+E7 mRNA NAA+probe Ql (Cvx)
Consumer Name Alpha Get Info
HPV 16 E6+E7 MRNA, Cervix

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
4491

Member of these Panels

LOINC Long Common Name
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets
96068-2 HEDIS MY 2020 Value Sets
82457-3 Human papilloma virus 16 and 18+45 E6+E7 mRNA panel - Cervix by NAA with probe detection

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) mRNA del virus 16E6+E7 del papiloma humano:PrThr:Punto temporal:Cuello uterino:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) ARNm del virus del papiloma humano 16 E6 + E7:Presencia o umbral:Punto temporal:Cuello uterino:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Papillomavirus humain 16 ARNm E6+E7:Présence/Seuil:Ponctuel:Col de l'utérus:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Papilloma virus umano 16 E6+E7 mRNA:PrThr:Pt:Cvx:Ord:Sonda.amp.tar
Synonyms: Cervice uterina Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Humaan papilloma virus 16 E6+E7 mRNA:aanwezigheid:moment:cervix:ordinaal:probe-detectie
Synonyms: baarmoederhals probe.amp.tar
zh-CN Chinese (China) 人乳头瘤病毒 16 E6+E7 mRNA:存在情况或阈值:时间点:子宫颈:序数型:探针法.基因扩增.靶向
Synonyms: HPV 16 E6+E7 mRNA;HPV 高危型 mRNA;人乳头状瘤病毒 高危型 mRNA HPV 16;HPV 16 型;HPV16;人类乳头瘤病毒 16 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV;人乳头瘤病毒（Human papilloma virus，HPV）;人类乳头瘤病毒;生殖器疣 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 宫颈;生殖道 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82456-5