LOINC
Version 2.66

13949-3Cytomegalovirus IgG Ab [Presence] in Serum or Plasma by ImmunoassayActive

Component
Cytomegalovirus Ab.IgG
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IA

Additional Names

Short Name
CMV IgG SerPl Ql IA
Display Name Beta
CMV IgG IA Ql
Consumer Name Alpha
Cytomegalovirus (CMV) IgG Antibody, Blood

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.63
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser since this test can be performed on plasma specimens as well.
Order vs. Observation
Both
CDISC Lab Test
Yes

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets

Language Variants Get Info

zh-CNChinese (China)
巨细胞病毒 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
nl-NLDutch (Netherlands)
Cytomegalovirus As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay
et-EEEstonian (Estonia)
Tsütomegaloviirus antikehad.IgG:PrThr:Pt:S/P:Ord:IA
fr-BEFrench (Belgium)
Cytomégalovirus Anticorps. IgG:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:IA
fr-CAFrench (Canada)
Cytomégalovirus , IgG:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:IA
fr-FRFrench (France)
Cytomegalovirus Ab.IgG:PrThr:Pt:Ser/Plas:Ord:IA
fr-CHFrench (Switzerland)
S--Cytomegalovirus, IgG; ; EIA
de-DEGerman (Germany)
Cytomegalievirus Ak.IgG:AKnz:Pkt:Ser:Ord:EIA
de-CHGerman (Switzerland)
S--Zytomegalovirus, IgG; ; EIA
it-ITItalian (Italy)
Citomegalovirus , Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA
it-CHItalian (Switzerland)
S--Cytomegalovirus, IgG; ; EIA
ko-KRKorean (Korea, Republic of)
거대세포바이러스 항체.면역글로불린 G:임의농도:검사시점:혈청:순위척도:효소면역측정법
pt-BRPortuguese (Brazil)
Citomegalovírus Ac.IgG:ACnc:Pt:Soro:Ord:Imunoensaio
ru-RURussian (Russian Federation)
Цитомегаловирус Ат.IgG:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA
es-ARSpanish (Argentina)
[anticuerpo anti - ] citomegalovirus [Ac].IgG [Inmunoglobulina G]:concentración arbitraria:punto en el tiempo:suero:ordinal:enzimoinmunoanálisis
es-ESSpanish (Spain)
Citomegalovirus IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-CHSpanish (Switzerland)
S--Cytomegalovirus, IgG; ; EIA
tr-TRTurkish (Turkey)
Cytomegalovirus Ab.IgG:MevcEşik:Zmlı:Ser/Plaz:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13949-3