LOINC
Version 2.73

15346-0Aldosterone [Mass/volume] in Serum or Plasma --30 minutes post XXX challengeActive

Part Descriptions

LP14377-3   Aldosterone
Aldosterone is a steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone also stimulates H+ secretion by intercalated cells in the collecting duct, regulating plasma bicarbonate (HCO3-) levels and its acidbase balance. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Aldosterone (Wikipedia)

LP14377-3   Aldosterone
Used to detect hyper and hypo aldosteronisnm. Hypoaldosteronism can occur in any condition that causes destruction or dysfunction of the adrenal gland.1,2,4 Hypoaldosterism can be due to primary adrenal insufficiency , congenital adrenal hypoplasia, acquired secondary aldosterone deficiency (hyporeninemic hypoaldosteronism), and acquired Hyporeninemic hypoaldosteronism is the most common form of isolated hypoaldosteronism and is results from impaired renin release from the kidney. Congenital hypoaldosteronism caused by inherited enzymatic defects in aldosterone biosynthesis are rare. Corticosterone methyloxidase I (CMO I) deficiency is associated with elevated serum levels of corticosterone and low levels of 18-hydroxy-corticosterone and aldosterone. Corticosterone methyloxidase II (CMO II) deficiency produces high levels of 18-hydroxy-corticosterone, the immediate precursor of aldosterone.
Acquired primary hypoaldosteronism can be caused by the administration of heparin. Also, persistently hypotensive, critically ill patients with sepsis, pneumonia, peritonitis, cholangitis, and liver failure can have inappropriately low plasma aldosterone concentrations in relation to elevated plasma renin activity. Primary hyperaldosteronism, also referred to as Conn syndrome, is due to overproduction of aldosterone by one or both of the adrenal glands. Some recent studies suggest that 10% to 15% of Hyper thyroidism cases are due to (or associated with ) primary hyperaldosteronism. Secondary hyperaldosteronism is relatively common and can occur as the result of any condition that decreases blood flow to the kidneys (ie, renal artery stenosis), decreases blood pressure, or lowers plasma sodium levels. Secondary hyperaldosteronism may also be seen with cirrhosis, congestive heart failure. and toxemia of pregnancy. Several studies have suggested that high-normal aldosterone levels predict development of high blood pressure in normotensive subjects and that increased aldosterone action contributes to hypertension, cardiovascular fibrosis, and cardiac hypertrophy. Source: Regenstrief Institute

Fully-Specified Name

Component
Aldosterone^30M post XXX challenge
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Aldost 30M p chal SerPl-mCnc
Display Name
Aldosterone 30 Min post Unsp challenge [Mass/Vol]
Consumer Name Alpha
Aldosterone 30 min after challenge, Blood

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Groups

LG50719-0 Aldosterone^30M post XXX challenge|Pt|Ser/Plas

Language Variants Get Info

zh-CNChinese (China)
醛固酮^在XXX刺激之后30分钟:质量浓度:时间点:血清/血浆:定量型:
nl-NLDutch (Netherlands)
aldosteron^30 minuten na XXX belasting:massa/volume:moment:serum of plasma:kwantitatief:
et-EEEstonian (Estonia)
Aldosteroon^30 minutit pärast XXX manustamist:MCnc:Pt:S/P:Qn:
fr-BEFrench (Belgium)
Aldostérone^30 min post test de provocation XXX:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CAFrench (Canada)
Aldostérone^30 min post test de provocation XXX:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)
Aldostérone T30min après épreuve:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)
Aldosterone^30Minuti post XXX provocazione:MCnc:Pt:Siero/Plasma:Qn:
ko-KRKorean (Korea, Republic of)
알도스테론^XXX유발 후 30 분:질량농도:검사시점:혈청/혈장:정량:
pt-BRPortuguese (Brazil)
Aldosterona^30 min após administração de XXX:MCnc:Pt:Sor/Plas:Qn:
ru-RURussian (Russian Federation)
Альдостерон^30 минут после XXX пробы:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
es-ARSpanish (Argentina)
aldosterona^30 minutos después de la provocación con XXX:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-MXSpanish (Mexico)
Aldosterona ^30 M después del desafío XXX:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ESSpanish (Spain)
Aldosterona^30 minutos pos provocación XXX:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
tr-TRTurkish (Turkey)
Aldosteron^30dk snr XXX girişimi:KütlKons:Zmlı:Ser/Plaz:Kant:

Example Units

Unit Source
ng/dL Example UCUM Units
ng/dL REGENSTRIEF

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