LOINC
Version 2.68

1975-2Bilirubin.total [Mass/volume] in Serum or PlasmaActive

Term Description

Method can be DIRECT SPECTOPHOTOMETRY, WET CHEMISTRY or DRY SLIDE (TBIL)
Source: Regenstrief LOINC

Part Description

LP15448-1   Bilirubin
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin). Source: Regenstrief LOINC

Fully-Specified Name

Component
Bilirubin
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Bilirub SerPl-mCnc
Display Name
Bilirubin [Mass/Vol]

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.68
Order vs. Observation
Both
Common US Lab Results Rank
21
Common Orders Rank
221
CDISC Lab Test
Yes

Associated Observations

This panel contains a collection of ask-at-order entry questions and associated observations that may be included within various PhenX protocols for biomarker testing. Each protocol varies as to the items asked & recorded, so not all terms will be used but are displayed together for users to find the appropriate LOINCs.

LOINC Name R/O/C Cardinality Example UCUM Units
95405-7 Assay related variables panel
Indent30525-0 Age a
Indent46098-0 Sex
Indent66165-2 Last ate or drank anything other than plain water [Date and time]
Indent80331-2 Date and time of last void {clock_time}
Indent66177-7 Do you have hemophilia?
Indent94741-6 Cancer chemotherapy received in the past 4W
Indent66178-5 Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66504-2 Exclusion Criteria
Indent41395-5 Collection date of Urine
Indent74751-9 Collection time of Urine {clock_time}
Indent94331-6 Specimen Collection procedure comment
Indent95044-4 Patient refused specimen collection
Indent94846-3 History of Specimen collection problem
Indent94847-1 Reason specimen not collected
Indent77301-0 Reason care action performed or not
Indent66180-1 Was blood drawn?
Indent66181-9 Was full sample obtained?
Indent94330-8 Specimen Processing comment
Indent8251-1 Service comment
Indent85069-3 Lab test method [Type]
Indent66200-7 Repeatability of the assay {ratio}
Indent66201-5 Coefficient of variation for the assay {CV}
Indent66208-0 Make of the equipment used to perform...
Indent74719-6 Manufacturer of the equipment used
Indent74720-4 Device name

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Total bilirubin = direct + indirect Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations
Webcontent Lab Tests Online®Copyright Copyright © 2001-2019 American Association for Clinical Chemistry Bilirubin

Member of these Panels

LOINC Long Common Name
34543-9 Bilirubin direct and total panel [Mass/volume] - Serum or Plasma
24322-0 Comprehensive metabolic 1998 panel - Serum or Plasma
24323-8 Comprehensive metabolic 2000 panel - Serum or Plasma
24324-6 Hepatic function 1996 panel - Serum or Plasma
24325-3 Hepatic function 2000 panel - Serum or Plasma
48796-7 Hepatitis C virus FibroSURE panel - Serum or Plasma
78698-8 Liver fibrosis score panel - Serum or Plasma Calculated by HepaScore
54232-4 Metabolic panel.large animal - Serum or Plasma
54233-2 Metabolic panel.small animal - Serum or Plasma
93691-4 Nonalcoholic steatohepatitis and fibrosis panel - Serum or Plasma

Member of these Groups

LG6199-6 Bilirubin|MCnc|Pt|ANYBldSerPl
LG49848-1 Bilirubin|Pt|Ser/Plas|584.673 g/mole

Language Variants Get Info

zh-CNChinese (CHINA)
胆红素:质量浓度:时间点:血清/血浆:定量型:
nl-NLDutch (NETHERLANDS)
bilirubine:massa/volume:moment:serum of plasma:kwantitatief:
et-EEEstonian (ESTONIA)
Bilirubiin:MCnc:Pt:S/P:Qn:
fr-BEFrench (BELGIUM)
Bilirubine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CAFrench (CANADA)
Bilirubine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (FRANCE)
Bilirubine:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
de-DEGerman (GERMANY)
Bilirubin:MKnz:Pkt:Ser/Plas:Qn:
el-GRGreek (GREECE)
Χολερυθρίνη:Συγκέντρωση μάζας:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
it-ITItalian (ITALY)
Bilirubina:MCnc:Pt:Siero/Plasma:Qn:
ko-KRKorean (KOREA, REPUBLIC OF)
빌리루빈:질량농도:검사시점:혈청/혈장:정량:
pt-BRPortuguese (BRAZIL)
Bilirrubina:MCnc:Pt:Sor/Plas:Qn:
ru-RURussian (RUSSIAN FEDERATION)
Билирубин:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
es-ARSpanish (ARGENTINA)
bilirrubina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (SPAIN)
Bilirrubina:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
tr-TRTurkish (TURKEY)
Bilirubin:KütlKons:Zmlı:Ser/Plaz:Kant:

Example Units

Unit Source
mg/dL Example UCUM Units
mg/dL REGENSTRIEF

Units and Range

Range
mg/dL:[0.3,1.0];
Unit Type

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=1975-2