LOINC
Version 2.72

21598-8Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detectionActive

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus DNA
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
VZV DNA CSF Ql NAA+probe
Display Name
VZV DNA NAA+probe Ql (CSF)
Consumer Name Alpha
Varicella zoster virus (VZV; Chickenpox), Spinal fluid

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.63
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
99087-9 Meningitis+Encephalitis pathogens panel - Cerebral spinal fluid by NAA with probe detection

Member of these Groups

LG32750-8 Varicella zoster virus

Language Variants Get Info

zh-CNChinese (China)
水痘带状疱疹病毒 DNA:存在情况或阈值:时间点:脑脊液:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
varicella-zostervirus DNA:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:moleculaire techniek (PCR)
fr-BEFrench (Belgium)
Virus varicelle-zona ADN:PrThr:Temps ponctuel:LCR:Ordinal:Sonde avec amplification de la cible
fr-CAFrench (Canada)
Virus varicelle-zona , ADN:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Sonde avec amplification de la cible
fr-FRFrench (France)
Varicelle zona virus ADN:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:PCR amplification de cible
de-DEGerman (Germany)
Varicella-Zoster-Virus DNA:Nachweis oder Schwellenwert:Zeitpunkt:Zerebrospinalflüssigkeit:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GRGreek (Greece)
Ιός ανεμευλογιάς-έρπητα ζωστήρα DNA:PrThr:Χρονική στιγμή:ΕΝΥ:Τακτική:Ανιχνευτής με ενίσχυση στόχου
it-ITItalian (Italy)
Varicella zoster, virus DNA:PrThr:Pt:LCS:Ord:Sonda.amp.tar
ko-KRKorean (Korea, Republic of)
수두 대상포진 바이러스 디옥시리보핵산:임의농도:검사시점:뇌척수액:순위척도:DNA 탐색자.증폭.표적
pt-BRPortuguese (Brazil)
Varicella zoster vírus DNA:ACnc:Pt:LCR:Ord:Sonda com limite de detecção da amplificação de alvo
ru-RURussian (Russian Federation)
Varicella zoster вирус ДНК:PrThr:ТчкВрм:ЦСЖ:Пор:Проба.усил.миш
es-ARSpanish (Argentina)
ADN del virus Varicela-zoster:concentración arbitraria:punto en el tiempo:líquido cefalorraquídeo:ordinal:sonda.amplificación.blanco
es-MXSpanish (Mexico)
ADN del virus de la varicela zóster:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ESSpanish (Spain)
Virus Varicella zoster ADN:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Varicella zoster virüsü DNA:MevcEşik:Zmlı:BOS:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=21598-8