Version 2.74

Part Description

LP15735-1   Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase. Source: Regenstrief LOINC

Fully-Specified Name

Component
Methylmalonate
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Methylmalonate SerPl-mCnc
Display Name
Methylmalonate [Mass/Vol]
Consumer Name Alpha
Methylmalonate, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank
5054

Member of these Groups

LOINC Group Group Name
LG47301-3 Methylmalonate|Pt|Ser/Plas|118.088 g/mole

Language Variants

Tag Language Translation
zh-CN Chinese (China) 甲基丙二酸:质量浓度:时间点:血清/血浆:定量型:
Synonyms: MMA;丙二酸二甲酯;甲基丙二酸盐;甲基丙二酸盐/酯;甲基丙二酸酯 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆
es-AR Spanish (Argentina) metilmalonato:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
fr-CA French (Canada) Méthylmalonate:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
et-EE Estonian (Estonia) Metüülmalonaat:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
pt-BR Portuguese (Brazil) Metilmalonato:MCnc:Pt:Sor/Plas:Qn:
Synonyms: MMA; Methylmalonic acid; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
de-DE German (Germany) Methylmalonat:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
Synonyms: Methylmalonsäure
es-ES Spanish (Spain) Metilmalonato:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
ko-KR Korean (Korea, Republic Of) 메틸말로네이트:질량농도:검사시점:혈청/혈장:정량:
it-IT Italian (Italy) Metilmalonato:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
el-GR Greek (Greece) Μεθυλμαλονικό:Συγκέντρωση μάζας:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
fr-FR French (France) Méthylmalonate:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
tr-TR Turkish (Turkey) Metilmalonat:KütlKons:Zmlı:Ser/Plaz:Kant:
ru-RU Russian (Russian Federation) Метилмалонат:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
nl-NL Dutch (Netherlands) methylmalonaat:massa/volume:moment:serum of plasma:kwantitatief:
fr-BE French (Belgium) Méthylmalonate:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
es-MX Spanish (Mexico) Malonato de metilo:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:

Example Units

Unit Source
ug/dL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR®

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=2629-4