LOINC
Version 2.67

29778-8West Nile virus IgM Ab [Presence] in Unspecified specimen by ImmunoassayActive

Part Description

LP28423-9   West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available. [PMID: 12089283] [PMID: 23034323] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, IgM

Fully-Specified Name

Component
West Nile virus Ab.IgM
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
IA

Additional Names

Short Name
WNV IgM XXX Ql IA
Display Name
West Nile virus IgM IA Ql (Unsp spec)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.04
Last Updated
Version 2.56
Change Reason
The Property was changed from ACnc according to the current LOINC model to more accurately reflect the property for ordinal terms whose results are reported as present or absent.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG32768-0 West Nile virus

Language Variants Get Info

zh-CNChinese (CHINA)
西尼罗河病毒 抗体.IgM:存在情况或阈值:时间点:XXX:序数型:免疫测定法
nl-NLDutch (NETHERLANDS)
West-Nijlvirus As.IgM:aanwezigheid:moment:XXX:ordinaal:immunoassay
fr-BEFrench (BELGIUM)
Virus du Nil occidental Anticorps. IgM:PrThr:Temps ponctuel:XXX:Ordinal:IA
fr-CAFrench (CANADA)
Virus du Nil occidental , IgM:Présence-Seuil:Temps ponctuel:XXX:Ordinal:IA
fr-FRFrench (FRANCE)
Virus du Nil occidental Ac IgM:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Immunoanalyse
it-ITItalian (ITALY)
Nilo occidentale, virus , Ab.IgM:PrThr:Pt:XXX:Ord:IA
ko-KRKorean (KOREA, REPUBLIC OF)
웨스트 나일 바이러스 항체.면역글로불린 M:임의농도:검사시점:XXX:순위척도:효소면역측정법
pt-BRPortuguese (BRAZIL)
Vírus do Nilo Ocidental Ac.IgM:ACnc:Pt:XXX:Ord:Imunoensaio
ru-RURussian (RUSSIAN FEDERATION)
Западный Нил вирус Ат.IgM:PrThr:ТчкВрм:XXX:Пор:IA
es-ARSpanish (ARGENTINA)
anticuerpo contra virus del Nilo occidental.inmunoglobulina M:concentración arbitraria:punto en el tiempo:XXX:ordinal:enzimoinmunoanálisis
es-ESSpanish (SPAIN)
Virus Nilo Occidental IgM:PrThr:Punto temporal:XXX:Ord:IA
tr-TRTurkish (TURKEY)
Batı Nil virüsü Ab.IgM:MevcEşik:Zmlı:XXX:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29778-8