Version 2.73

29860-4Cardiolipin Ab [Presence] in SerumActive

Part Descriptions

LP14126-4   Cardiolipin
Cardiolipin (bisphosphatidyl glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid. It is typically present in metabolically active cells of the heart and skeletal muscle. It has also been observed in certain bacterial membranes. It serves as an insulator and stabilizes the activity of protein complexes important to the electron transport chain. Cardiolipin is a double phospholipid because it has four fatty acid tails, instead of the usual two. Barth syndrome, a rare genetic disorder, is a mutation in the gene coding for tafazzin, an enzyme involved in the biosynthesis of cardiolipin. Females heterozygous for the trait are not affected. Individuals with this condition have abnormal mitochondria and they cannot sustain adequate production of ATP. Cardiomyopathy and general weakness are common to these patients. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Cardiolipin (Wikipedia)

LP21333-7   Cardiolipin Ab
Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases including syphilis, antiphospholipid syndrome, livedoid vasculitis, vertebrobasilar insufficiency, Behçet's syndrome, idiopathic spontaneous abortion, and systemic lupus erythematosus(SLE). They are a form of anti-mitochondrial antibody. In SLE, The anti-DNA antibodies and anti-cardiolipin act independently. In rheumatoid arthritis with systemic sclerosis (scleroderma) these antibodies may tie two conditions together.
Anti-cardiolipin antibodies can be classified in two ways:
As IgM, IgG or IgA
As β2-glycoprotein dependent or independent
In autoimmune disease ACA are beta-2 glycoprotein dependent
syphilis ACA are beta-2 glycoprotein independent and can be assayed using the VDRL test Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Cardiolipin Ab

Additional Names

Short Name
Cardiolipin Ab Ser Ql
Display Name
Cardiolipin Ab Ql (S)
Consumer Name Alpha
Cardiolipin antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.04
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Common US Lab Results Rank

Language Variants Get Info

zh-CNChinese (China)
心磷脂 抗体:存在情况或阈值:时间点:血清:序数型:
nl-NLDutch (Netherlands)
cardiolipine As:aanwezigheid:moment:serum:ordinaal:
et-EEEstonian (Estonia)
Kardiolipiin antikehad:PrThr:Pt:S:Ord:
fr-BEFrench (Belgium)
Cardiolipine Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
fr-CAFrench (Canada)
Cardiolipine , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FRFrench (France)
Cardiolipine anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
de-DEGerman (Germany)
Cardiolipin Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:
it-ITItalian (Italy)
Cardiolipina Ab:PrThr:Pt:Siero:Ord:
ko-KRKorean (Korea, Republic of)
카디오리핀 항체:임의농도:검사시점:혈청:순위척도:
pt-BRPortuguese (Brazil)
Cardiolipina Ac:ACnc:Pt:Soro:Ord:
ru-RURussian (Russian Federation)
Кардиолипин Ат:PrThr:ТчкВрм:Сыв:Пор:
es-ARSpanish (Argentina)
anticuerpo anticardiolipina:concentración arbitraria:punto en el tiempo:suero:ordinal:
es-MXSpanish (Mexico)
Cardiolipin Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:
es-ESSpanish (Spain)
Cardiolipinas Anticuerpos:PrThr:Punto temporal:Suero:Ord:
tr-TRTurkish (Turkey)
Kardiyolipin Ab:MevcEşik:Zmlı:Ser:Srl:

LOINC FHIR® API Example - CodeSystem Request Get Info