Version 2.73

3206-0Coagulation factor VIII inhibitor [Presence] in Platelet poor plasma by Coagulation assayActive

Part Descriptions

LP29023-6   Coagulation factor VIII inhibitor
Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites [PMID:23610614]. Source: Regenstrief LOINC

LP14587-7   Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Coagulation factor VIII inhibitor

Additional Names

Short Name
Fact VIII Inhib PPP Ql
Display Name
Coagulation factor VIII inhibitor Coag Ql (PPP)
Consumer Name Alpha
Coagulation Factor VIII Inhibitor, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 1.0
Last Updated
Version 2.73
Change Reason
Changed Property from "ACnc" to "Pr" (Presence) to clarify that results (e.g. pos/neg, present/absent) are based on the presence of the inhibitor.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Common US Lab Results Rank

Member of these Panels

LOINC Long Common Name
96456-9 Coagulation factor VIII activity and inhibitor panel - Platelet poor plasma by Coagulation assay

Language Variants Get Info

zh-CNChinese (China)
凝血因子 VIII 抑制剂:存在情况或阈值:时间点:贫血小板血浆:序数型:凝血功能分析
nl-NLDutch (Netherlands)
stollingsfactor VIII remmer:aanwezigheid:moment:plaatjesarm plasma:ordinaal:stollingsmethode
et-EEEstonian (Estonia)
VIII faktori inhibiitor:PrThr:Pt:PPP:Ord:Koagulomeetria
fr-BEFrench (Belgium)
Inhibiteur du facteur VIII:PrThr:Temps ponctuel:Plasma pauvre en plaquettes:Ordinal:Test de coagulation
fr-CAFrench (Canada)
Inhibiteur du facteur VIII:Présence-Seuil:Temps ponctuel:Plasma pauvre en plaquettes:Ordinal:Test de coagulation
fr-FRFrench (France)
Facteur VIII inhibiteur:Présence/Seuil:Ponctuel:Plasma pauvre en plaquettes:Qualitatif:Coagulation
de-DEGerman (Germany)
Gerinnungsfaktor VIII-Inhibitor:Nachweis oder Schwellenwert:Zeitpunkt:Thrombozytenarmes Plasma:Ordinal:Gerinnungstest
it-ITItalian (Italy)
Fattore di coagulazione VIII, inibitore:PrThr:Pt:PPP:Ord:Coag
ko-KRKorean (Korea, Republic of)
응고 인자 VIII 억제인자:임의농도:검사시점:혈소판제거혈장:순위척도:응고검사
pl-PLPolish (Poland)
inhibitor Czynnika krzepniecia VIII:obecność lub wartość progowa:Punkt w czasie:Osocze ubogopłytkowe:Porządkowy:Test krzepnięcia
pt-BRPortuguese (Brazil)
Fator de coagulação VIII inibidor:ACnc:Pt:PPPQ:Ord:Coagulação
ru-RURussian (Russian Federation)
Коагуляции фактор VIII ингибитор:PrThr:ТчкВрм:ОПП:Пор:Коаг
es-ARSpanish (Argentina)
inhibidor de factor de coagulación VIII:concentración arbitraria:punto en el tiempo:plasma desplaquetado:ordinal:coagulación
es-MXSpanish (Mexico)
Inhibidor del factor VIII de la coagulación:Presencia o umbral:Punto temporal:Plasma pobre en plaquetas:Ordinal:Ensayo de coagulación
es-ESSpanish (Spain)
Factor de coagulación VIII inhibido:PrThr:Punto temporal:Plasma pobre en plaquetas:Ord:Coagulativo
tr-TRTurkish (Turkey)
Koagülasyon faktörü VIII inhibitörü:MevcEşik:Zmlı:TFkP:Srl:Koag

LOINC FHIR® API Example - CodeSystem Request Get Info