LOINC
Version 2.66

32283-4Valproate Free/Valproate.total in Serum or PlasmaActive

Component
Valproate.free/Valproate.total
Property
MFr
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Valproate Free MFr SerPl
Display Name Beta
Valproate Free/Valproate.total [Mass fraction]
Consumer Name Alpha
Free Valproate/Valproate.total, Blood

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug [PMID: 6636249] . For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.07
Last Updated
Version 2.30
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets

Language Variants Get Info

zh-CNChinese (China)
2-丙基戊酸.游离型/2-丙基戊酸.总计:质量分数:时间点:血清/血浆:定量型:
nl-NLDutch (Netherlands)
valproaat.vrije/valproaat.totaal:massafractie:moment:serum of plasma:kwantitatief:
et-EEEstonian (Estonia)
Valproaat.vaba/valproaat.üld:MFr:Pt:S/P:Qn:
fr-BEFrench (Belgium)
Valproate.libre/Valproate.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CAFrench (Canada)
Valproate.libre/Valproate.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)
Valproate.free/Valproate.total:MFr:Pt:Ser/Plas:Qn:
it-ITItalian (Italy)
Valproato.libero/Valproato.totale:MFr:Pt:Siero/Plasma:Qn:
ko-KRKorean (Korea, Republic of)
유리벨프로에이트/총벨프로에이트:질량분획:검사시점:혈청/혈장:정량:
pt-BRPortuguese (Brazil)
Valproato.livre/Valproato.total:MFr:Pt:Sor/Plas:Qn:
ru-RURussian (Russian Federation)
Вальпроат.свободный/Вальпроат.общий:МассДол:ТчкВрм:Сыв/Плаз:Колич:
es-ARSpanish (Argentina)
valproato.libre/valproato.total:fracción de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (Spain)
Valproico libre/Valproato total:Fracción de masa:Punto temporal:Suero o Plasma:Qn:
tr-TRTurkish (Turkey)
Valproat.serb/Valproat.total:KütlFr:Zmlı:Ser/Plaz:Kant:

Example Units

Unit Source
% Example UCUM Units
% REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=32283-4