33331-0
West Nile virus IgM Ab [Titer] in Serum
Active
Part Description
LP28423-9 West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available.[PMID: 12089283][PMID: 23034323]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- West Nile virus Ab.IgM
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- WNV IgM Titr Ser
- Display Name
- West Nile virus IgM (S) [Titer]
- Consumer Name Alpha
- West Nile virus IgM antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank
- 16424
Member of these Groups
| LOINC Group | Group Name |
|---|---|
| LG32768-0 | West Nile virus |
Language Variants
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 西尼罗河病毒 抗体.IgM: Synonyms: |
| es-AR | Spanish (Argentina) | anticuerpo contra virus del Nilo occidental.inmunoglobulina M: |
| fr-CA | French (Canada) | Virus du Nil occidental , IgM: |
| pt-BR | Portuguese (Brazil) | Vírus do Nilo Ocidental Ac.IgM: Synonyms: |
| es-ES | Spanish (Spain) | Virus Nilo Occidental IgM: |
| ko-KR | Korean (Korea, Republic Of) | 웨스트 나일 바이러스 항체.면역글로불린 M: |
| it-IT | Italian (Italy) | Nilo occidentale, virus Ab.IgM: Synonyms: |
| fr-FR | French (France) | West Nile virus Ac IgM: |
| tr-TR | Turkish (Turkey) | Batı Nil virüsü Ab.IgM: Synonyms: |
| ru-RU | Russian (Russian Federation) | Западный Нил вирус Ат.IgM: Synonyms: |
| nl-NL | Dutch (Netherlands) | West-Nijlvirus As.IgM: Synonyms: |
| fr-BE | French (Belgium) | Virus du Nil occidental Anticorps. IgM: Synonyms: |
| de-DE | German (Germany) | West-Nil-Virus Ak.IgM: |
| es-MX | Spanish (Mexico) | Ab.IgM del virus del Nilo Occidental: |
Example Units
| Unit | Source |
|---|---|
| titer | REGENSTRIEF |
| {titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR®
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=33331-0
LOINC Copyright
Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright