Version 2.73

33701-4Clostridium botulinum toxin A [Presence] in Specimen by Mouse bioassay neutralizationActive

Part Description

LP31258-4   Clostridium botulinum toxin A
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod found on plants, in soil, water and the intestinal tracts of animals. Eight exotoxins (A, B, C1, C2, D, E, F and G) have been identified, all of which interfere with neural transmission by blocking the release of acetylcholine, the principal neurotransmitter at the neuromuscular junction. The toxins are used in the clinical management of various spastic medical conditions, strabismus and focal dystonias, hemifacial spasms, headaches, hyper-salivation and hyperhidrosis. Type A is the most potent toxin. In 2002 it was approved by the U.S. Food and Drug Administration for cosmetological uses. It is administered by injection into muscles or glands with the effects lasting approximately three months. Most patients require multiple treatments over many years and some develop tolerance to the injections due to the development of neutralizing antibodies to the toxin. Side effects are minor and transient. [PMID:20418969] Source: Regenstrief LOINC

Fully-Specified Name

Clostridium botulinum toxin A
Mouse bioassay.neutralization

Additional Names

Short Name
C bot Tox A Spec Ql MA Nt
Display Name
C. botulinum toxin A Mouse bioassay neutralization Ql (Specimen)
Consumer Name Alpha
Clostridium botulinum toxin A, Specimen

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.09
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Common US Lab Results Rank

Member of these Groups

LG41628-5 Clostridium botulinum

Language Variants Get Info

zh-CNChinese (China)
肉毒梭菌毒素 A:存在情况或阈值:时间点:XXX:序数型:小鼠生物鉴定.中和作用
nl-NLDutch (Netherlands)
Clostridium botulinum toxine A:aanwezigheid:moment:XXX:ordinaal:muizen-bioassay.neutralisatie
fr-BEFrench (Belgium)
Toxine Clostridium botulinum A:PrThr:Temps ponctuel:XXX:Ordinal:Test biologique sur souris.neutralisation
fr-CAFrench (Canada)
Toxine Clostridium botulinum A:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Test biologique sur souris.neutralisation
fr-FRFrench (France)
Clostridium botulinum toxine A:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Test sur souris neutralisation
de-DEGerman (Germany)
Clostridium botulinum Toxin A:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Maus-Bioassay.Neutralisation
it-ITItalian (Italy)
Clostridium botulinum, tossina A:PrThr:Pt:XXX:Ord:Saggio biologico topo.neutralizzazione
ko-KRKorean (Korea, Republic of)
클로스트리디움 보튤리늄 독소 A:임의농도:검사시점:XXX:순위척도:쥐 중화 생물학적검정법
pt-BRPortuguese (Brazil)
Clostridium botulinum toxina A:ACnc:Pt:XXX:Ord:Bioensaio de neutralização murino
es-ARSpanish (Argentina)
toxina de Clostridium botulinum A:concentración arbitraria:punto en el tiempo:XXX:ordinal:bioanálisis en ratones.neutralización
es-MXSpanish (Mexico)
Toxina A de Clostridium botulinum:Presencia o umbral:Punto temporal:XXX:Ordinal:Neutralización de bioensayo en ratón
es-ESSpanish (Spain)
Toxina A del Clostridium botulinum:PrThr:Punto temporal:XXX:Ord:Bioensayo en ratones. Neutralización
tr-TRTurkish (Turkey)
Clostridium botulinum toksin A:MevcEşik:Zmlı:XXX:Srl:Sıçan biyoölçüm.nötralizasyon

LOINC FHIR® API Example - CodeSystem Request Get Info