Version 2.77

Part Descriptions

LP16473-8   Interleukin 5
Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is also a key mediator in eosinophil activation. IL-5 is a 115 amino acid (in man, 133 in the mouse) long TH2 cytokine which is part of the hematopoietic family.Interleukin-5 is also expressed by eosinophils and has been observed in the mast cells of asthmatic airways by immunohistochemistry. IL-5 expression is regulated by several transcription factors including GATA3. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP16473-8   Interleukin 5
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 5 is a 50,000-60,000 molecular weight glycoprotein originally called T Cell Replacing Factor. It is released primarily by activated T Cells. Its primary target cells are B cells and eosinophils. Interleukin 5 activates B cell differentiation. Its actions are similar to Interleukin 3. Interleukin 5 primes basophils for agonist-induced generation of Leukotriene C4. It is stimulated by Interleukin 2. Interleukin 5 stimulates growth and differentiation of eosinophil progenitor without influencing cells committed to neutrophils, basophils, or monocytes. It enhances responsiveness of eosinophils inducing polarization, shape change, chemotaxis, cytotoxity, oxygen radical release and prolongs survival. Source: Inter Science Institute, Inter Science Institute

Fully-Specified Name

Component
Interleukin 5
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Il5 SerPl-mCnc
Display Name
Interleukin 5 [Mass/Vol]
Consumer Name Alpha Get Info
Interleukin 5, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6808

Member of these Panels

LOINC Long Common Name
82335-1 Cytokines panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Interleukin-5:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
de-AT German (Austria) Synonyms: Interleukin-5
es-AR Spanish (Argentina) interleucina 5:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-MX Spanish (Mexico) Interleucina 5:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Interleuquina 5:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Interleukiin 5:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Interleukine-5:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Interleukine 5:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Il5
fr-CA French (Canada) Interleukine 5:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Interleuchina 5:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 인터루킨 5:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) interleukine 5:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Interleucina 5:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Il5; IL-5; B-Cell Growth Factor-II; Eosinophil Differentiation Factor; T-Cell Replacing Factor; IL5; BCGF-II; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; IL; Chemistry
ru-RU Russian (Russian Federation) Интерлейкин 5:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) İnterlökin 5:KütlKons:Zmlı:Ser/Plaz:Kant:
uk-UA Ukrainian (Ukraine) Інтерлейкін 5:Масова Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:
Synonyms: B-Cell Growth Factor-II; BCGF-II; Chemistry; Eosinophil Differentiation Factor; IL; IL5; IL-5; Level; Mass concentration; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; T-Cell Replacing Factor
zh-CN Chinese (China) 白细胞介素 5:质量浓度:时间点:血清/血浆:定量型:
Synonyms: B 细胞生长因子-II;BCGF-II;B-细胞生长因子-II;Il5;IL-5;T 细胞替代因子;T-细胞替代因子;嗜酸性粒细胞分化因子;白介素 5;白介素-5;白细胞介素-5;肥大细胞生长因子 IL 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 白介 白介素 白细胞介素（Interleukin，白介素，IL） 血清或血浆

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=33938-2