Version 2.68

36903-3Chlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Unspecified specimen by NAA with probe detectionActive

Part Description

LP115359-4   Chlamydia trachomatis & Neisseria gonorrhoeae
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type. Source: Regenstrief Help

Fully-Specified Name

Chlamydia trachomatis & Neisseria gonorrhoeae DNA

Additional Names

Short Name
C trach+GC DNA XXX NAA+probe
Display Name
C. trachomatis and N. gonorrhoeae DNA NAA+probe Nom (Unsp spec)

Basic Attributes

First Released
Version 2.13
Last Updated
Version 2.63
Change Reason
Changed + to & in Component because this is a Prid/Nom term that is used for assays that can detect and differentiate between the organisms.
Order vs. Observation
Common US Lab Results Rank
Common SI Lab Results Rank

Example Answer List LL1501-7

Source: Association of Public Health Laboratories

Answer Code Score Answer ID
Chlamydia trachomatis detected LA16153-1
Chlamydia trachomatis not detected LA16154-9
Chlamydia trachomatis inconclusive LA16155-6
Chlamydia trachomatis equivocal LA16157-2
Neisseria gonorrhoeae detected LA16150-7
Neisseria gonorrhoeae not detected LA16151-5
Neisseria gonorrhoeae inconclusive LA16152-3
Neisseria gonorrhoeae equivocal LA16156-4

Member of these Panels

LOINC Long Common Name
86636-8 Family planning report - FPAR 2.0 set
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets

Language Variants Get Info

zh-CNChinese (CHINA)
沙眼衣原体与淋病奈瑟菌 DNA:存在与否或特征标识:时间点:XXX:名义型:探针法.基因扩增.靶向
Chlamydia trachomatis & Neisseria gonorrhoeae DNA:identificator:moment:XXX:nominaal:moleculaire techniek (PCR)
fr-CAFrench (CANADA)
Chlamydia trachomatis & Neisseria gonorrhoeae , ADN:Présence ou identité:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
fr-FRFrench (FRANCE)
Chlamydia trachomatis et Neisseria gonorrhoeae ADN:Identification:Ponctuel:Milieux divers:Résultat nominal:PCR amplification de cible
it-ITItalian (ITALY)
Chlamydia trachomatis & Neisseria gonorrhoeae , DNA:Prid:Pt:XXX:Nom:Sonda.amp.tar
클라미디아 트라코마티스+임균 디옥시리보핵산:존재:검사시점:XXX:명칭결과:DNA 탐색자.증폭.표적
pt-BRPortuguese (BRAZIL)
Chlamydia trachomatis+Neisseria gonorrhoeae DNA:Ident:Pt:XXX:Nom:Sonda com limite de detecção da amplificação de alvo
Chlamydia trachomatis & Neisseria gonorrhoeae ДНК:ПрИд:ТчкВрм:XXX:Ном:Проба.усил.миш
es-ARSpanish (ARGENTINA)
[anticuerpo anti - ] Neisseria gonorrhoeae [Ac]:presencia o identidad:punto en el tiempo:XXX:Nominal:sonda.amplificación.blanco
es-ESSpanish (SPAIN)
Chlamydia trachomatis & Neisseria gonorrhoeae ADN:Presencia o identidad:Punto temporal:XXX:Nom:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info