Version 2.76

Part Description

LP35835-5   Clostridium botulinum toxin A botA gene
Clostridium botulinum is a gram positive, anaerobic bacterium that produces a potent neurotoxin that binds to presynaptic nerve terminals preventing release of acetylcholine, blocking neurotransmission. C. botulinum Toxin types A, B, E, F can produce severe, potentially fatal illness in humans. Types C and D are pathogenic in avians, and the pathogenicity of type G is unknown. Illness can occur as foodborne botulism which occurs when a person ingests pre-formed toxin that leads to illness within a few hours to days. Foodborne botulism is a public health emergency because the contaminated food may still be available to other persons besides the patient. Infant botulism occurs in a small number of susceptible infants each year who become infected C. botulinum bacteria grow in their intestinal tract. Wound botulism occurs when open skin lesions or wounds are infected with C. botulinum that secretes the toxin. C. botulinum and the associated toxins are on the Department of Health and Human Services and the USDA list of Select Agents that could be used as weapons of bioterrorism. Source: Regenstrief LOINC

Fully-Specified Name

Component
Clostridium botulinum toxin A botA gene
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
C botA gene Spec Ql NAA+probe
Display Name
C. botulinum toxin A botA gene NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info
Clostridium botulinum toxin A botA gene, Specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.69
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses around the gene name in the Component based on the current LOINC model.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
80827-9 Clostridium botulinum and Clostridium baratii toxins gene panel - Specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG41628-5 Clostridium botulinum

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Clostridium botulinum Toxin A botA-Gen:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Gen de la toxina A Clostridium botulinum (botA):PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Gen botA de la toxina A de Clostridium botulinum:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Gène A toxine Clostridium botulinum botA:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Clostridium botulinum toxine A botA gène:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
fr-BE French (Belgium) Gène A toxine Clostridium botulinum:PrThr:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
Synonyms: Clostridium botulinum A. Toxine Clostridium botulinum. Gène toxine A Clostridium botulinum.Toxine
it-IT Italian (Italy) Clostridium botulinum, gene tossina A:PrThr:Pt:XXX:Ord:Sonda.amp.tar
Synonyms: Gene di tossina A di Clostridium botulinum Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Tossina A di Clostridium botulinum Tossina di Clostridium botulinum
ko-KR Korean (Korea, Republic Of) 클로스트리디움 보튤리늄 독소 A 유전자:임의농도:검사시점:XXX:순위척도:DNA 탐색자.증폭.표적
nl-NL Dutch (Netherlands) Clostridium botulinum toxine A-gen:aanwezigheid:moment:XXX:ordinaal:probe-detectie
Synonyms: clostridium botulinum toxine A gen probe.amp.tar
pt-BR Portuguese (Brazil) Clostridium botulinum toxina A gene:ACnc:Pt:XXX:Ord:Sonda com limite de detecção da amplificação de alvo
Synonyms: ; C bot Tox A gene; botA; Botox; C botulinum; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Microbiology
ru-RU Russian (Russian Federation) Clostridium botulinum токсин A ген:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Clostridium botulinum toksin A geni:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 肉毒梭菌毒素 A botA 基因:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向
Synonyms: A 型 botA;肉毒杆菌毒素 A botA 基因;肉毒梭状芽孢杆菌毒素 A botA 基因 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 肉毒 A;肉毒 A 型;肉毒梭菌毒素 A 型;肉毒梭菌神经毒素 A;肉毒梭菌神经毒素 A 型;肉毒毒素 A;肉毒毒素 A 型 肉毒;肉毒梭菌神经毒素;肉毒毒素;肉毒芽孢梭菌毒素 肉毒梭状芽胞杆菌;肉毒芽孢梭菌 脱氧核糖核酸探针 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=41631-3