43279-9Hepatitis B Virus YMDD [Presence] in Serum or Plasma by NAA with probe detectionActive
Part Description
LP36432-0 Hepatitis B virus YMDD mutation
In hepatitis B, lamivudine resistance was first described in the YMDD locus of the HBV reverse transcriptase gene. The HBV reverse transcriptase gene is 344 amino acids long and occupies codons 349 to 692 on the viral genome. The most commonly encountered resistance mutations are M204V/I/S. The change in amino acid sequence from YMDD to YIDD results in a 3.2 fold reduction in the error rate of the reverse transcriptase, which correlates with a significant growth disadvantage of the virus.
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Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Hepatitis B virus YMDD mutation
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- HBV YMDD Mut SerPl Ql NAA+probe
- Display Name
- HBV YMDD NAA+probe Ql
- Consumer Name Alpha
- Hepatitis B virus (HBV) YMDD, Blood
Example Answer List LL744-4
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.65
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Groups
| LG32752-4 | Hepatitis B virus |
Language Variants Get Info
- zh-CNChinese (China)
- 乙型肝炎病毒 YMDD 突变:
存在情况或阈值: 时间点: 血清/血浆: 序数型: 探针法.基因扩增.靶向 - nl-NLDutch (Netherlands)
- Hepatitis B-virus YMDD mutatie:
aanwezigheid: moment: serum of plasma: ordinaal: moleculaire techniek (PCR) - fr-BEFrench (Belgium)
- Mutants YMDD du virus de l'hépatite B:
PrThr: Temps ponctuel: Sérum/Plasma: Ordinal: Sonde avec amplification de la cible - fr-CAFrench (Canada)
- Mutants YMDD du virus de l'hépatite B:
Présence-Seuil: Temps ponctuel: Sérum/Plasma: Ordinal: Sonde avec amplification de la cible - fr-FRFrench (France)
- Hépatite B virus mutation YMDD:
Présence/Seuil: Ponctuel: Sérum/Plasma: Qualitatif: PCR amplification de cible - it-ITItalian (Italy)
- Epatite B virus, mutazione YMDD:
PrThr: Pt: Siero/Plasma: Ord: Sonda.amp.tar - pt-BRPortuguese (Brazil)
- Hepatite B vírus YMDD mutação:
Ident: Pt: Sor/Plas: Nom: Sonda com limite de detecção da amplificação de alvo - ru-RURussian (Russian Federation)
- Гепатит B вирус YMDD мутация:
PrThr: ТчкВрм: Сыв/Плаз: Пор: Проба.усил.миш - es-MXSpanish (Mexico)
- Virus de la hepatitis B YMDD:
Presencia o umbral: Punto temporal: Suero o Plasma: Ordinal: Amplificación de ácidos nucleicos con detección de sonda - es-ESSpanish (Spain)
- Gen GDAP1:
PrThr: Punto temporal: Suero o Plasma: Ord: Sonda con amplificación dirigida - tr-TRTurkish (Turkey)
- Hepatit B virüsü YMDD mutasyonu:
MevcEşik: Zmlı: Ser/Plaz: Srl: Prob.amf.hdf
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43279-9
LOINC Copyright
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