44316-8
DOPamine/Creatinine [Mass Ratio] in 24 hour Urine
Active
Part Descriptions
LP15543-9 DOPamine
Dopamine, a chemical naturally produced in the body, functions in the brain as a neurotransmitter, activating dopamine receptors. It is also a neurohormone released by the hypothalamus. As a hormone, it inhibits the release of prolactin from the anterior lobe of the pituitary. Dopamine can also be supplied as a medication to target the sympathetic nervous system, leading to increased heart rate and blood pressure. Because dopamine cannot cross the blood-brain barrier, however, when given as a drug it does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and Dopa-Responsive Dystonia, a synthetic precursor to dopamine such as L-DOPA can be given, since this will cross the blood-brain barrier.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Dopamine (Wikipedia)
LP15543-9 DOPamine
Dopamine is a member of the catecholamine (Neurotransmitters) family in the brain, and is a precursor to epinephrine (adrenaline) and norepinephrine (noradrenaline). Dopamine is synthesized in the body (mainly by nervous tissue and adrenal glands) first by the hydration of the amino acid tyrosine to DOPA by tyrosine hydroxylase and then by the decarboxylation of DOPA by aromatic-L-amino-acid decarboxylase.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Dopamine
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- DOPamine/Creatinine
- Property
- MRto
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- DOPamine/Creat 24h Ur
- Display Name
- DOPamine/Creatinine (24H U) [Mass ratio]
- Consumer Name Alpha Get Info
- DOPamine/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 14308
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG34580-7 | Dopamine/Creatinine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | DOPamina / Creatinina: |
| es-ES | Spanish (Spain) | Dopamina/Creatinina: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Dopamiin/kreatiniin: Synonyms: Kvantitatiivne Uriin |
| fr-CA | French (Canada) | Dopamine/Créatinine: |
| fr-FR | French (France) | Dopamine/créatinine: |
| fr-BE | French (Belgium) | Dopamine/Créatinine: Synonyms: Rapport de masse |
| it-IT | Italian (Italy) | Dopamina/Creatinina: Synonyms: 24 Ore Chimica Rapporto di Massa |
| nl-NL | Dutch (Netherlands) | dopamine/creatinine: Synonyms: 24U kreatinine |
| pt-BR | Portuguese (Brazil) | Dopamina/Creatinina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Допамин/Креатинин: Synonyms: Количественный Масс отношение |
| tr-TR | Turkish (Turkey) | Dopamin/Kreatinin: |
| zh-CN | Chinese (China) | 多巴胺/肌酐: Synonyms: 1天; |
Example Units
| Unit | Source |
|---|---|
| ug/g{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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