LOINC
Version 2.67

44786-2Aspartate aminotransferase [Enzymatic activity/volume] (Maximum value during study) in Serum or PlasmaActive

Term Description

Pyridoxal phosphate is a derivative of Vitamin B6 and is used by enzymes in all organisms. The majority of enzymes which depend on pyridoxal phosphate are associated with pathways involving amino acids, such as amino group transfer, decarboxylation and other important biochemical processes. [PMCID:1326353]
When measuring AST and/or ALT without pyridoxal-5-phosphate (P-5-P), the rate of the decrease of NADH is directly proportional to the AST/ALT (respectively)-activity in the specimen. Testing for AST and/or ALT with the addition of P-5-P stabilizes the transaminases in the specimen and avoids falsely low values in specimens of patients suffering from either myocardial infarction or liver disease, who have an insufficient amount of P-5-P in their blood.
Source: Regenstrief LOINC

Part Description

LP15426-7   Aspartate aminotransferase
Aspartate aminotransferase (AST) is an enzyme that is released by injured muscle cells and liver cell and is predominately found in the liver and heart. AST levels in the blood are most often used to monitor liver damage. AST is typically tested in conjunction with alanine aminotransferase (ALT) when a liver panel is ordered. High levels of AST in the bloodstream could indicate hepatitis, drug damage to the liver, cirrhosis, alcoholism, or other liver disorders. [Lab Tests Online:ast/tab/test] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Aspartate (Wikipedia)

Fully-Specified Name

Component
Aspartate aminotransferase
Property
CCnc
Time
Stdy^max
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
AST (Study max) SerPl-cCnc
Display Name
AST (Stdy maximum) [Catalytic activity/Vol]

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.54
Order vs. Observation
Observation

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2001-2019 American Association for Clinical Chemistry Aspartate Aminotransferase (AST)

Language Variants Get Info

zh-CNChinese (CHINA)
天冬氨酸氨基转移酶:催化浓度:检查过程持续时间^最大值:血清/血浆:定量型:
nl-NLDutch (NETHERLANDS)
aspartaataminotransferase:enzymatische activiteit/volume:onderzoek^maximum:serum of plasma:kwantitatief:
et-EEEstonian (ESTONIA)
Aspartaadi aminotransferaas:CCnc:Stdy^max:S/P:Qn:
fr-BEFrench (BELGIUM)
Aspartate aminotransférase, Transaminase GO:Concentration catalytique:Étude^maximum:Sérum/Plasma:Quantitatif:
fr-CAFrench (CANADA)
Aspartate aminotransférase:Concentration catalytique:Étude^maximun:Sérum/Plasma:Quantitatif:
fr-FRFrench (FRANCE)
Aspartate aminotransferase:CCnc:Stdy^max:Ser/Plas:Qn:
it-ITItalian (ITALY)
Aspartato aminotransferasi:CCnC:Studio^max:Siero/Plasma:Qn:
pt-BRPortuguese (BRAZIL)
Aspartato amino transferase:CCnc:Stdy^max:Sor/Plas:Qn:
ru-RURussian (RUSSIAN FEDERATION)
Аспартат аминотрансфераза:КаталКонц:Исслед^максимум:Сыв/Плаз:Колич:
es-ESSpanish (SPAIN)
Aspartato amino transferasa:Concentración Catalítica:Estudio^Valor maximo durante un intervalo:Suero o Plasma:Qn:
tr-TRTurkish (TURKEY)
Aspartat aminotransferaz:KtlKons:Çlşm^maks:Ser/Plaz:Kant:

Example Units

Unit Source
U/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=44786-2