LOINC
Version 2.67

47363-7Cytomegalovirus Ab [Presence] in Serum from Donor by HemagglutinationActive

Term Description

This test is intended to be used as a primary screening test for the diagnosis of infection with Cytomegalovirus (CMV). This test has been approved by the FDA for the screening of donors of human cells, tissues and tissue-based products. A Positive result is indicative of an infection with CMV, and may be used to disqualify a potential cell or tissue donor. This test is not intended to be used for routine clinical diagnostic testing. This test is required for all donors of "leukocyte-rich" human cells, tissues and tissue-based products
Source: Regenstrief LOINC

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab
Property
PrThr
Time
Pt
System
Ser^Donor
Scale
Ord
Method
HA

Additional Names

Short Name
CMV Ab Ser Donr Ql HA
Display Name
CMV Ab HA Ql (S donor)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets

Language Variants Get Info

zh-CNChinese (CHINA)
巨细胞病毒 抗体:存在情况或阈值:时间点:血清^供体:序数型:红细胞凝集试验法
nl-NLDutch (NETHERLANDS)
Cytomegalovirus As:aanwezigheid:moment:serum^donor:ordinaal:hemagglutinatie
et-EEEstonian (ESTONIA)
Tsütomegaloviirus antikehad:PrThr:Pt:S^doonor:Ord:HA
fr-BEFrench (BELGIUM)
Cytomégalovirus Ac:PrThr:Temps ponctuel:Sérum^Donneur:Ordinal:Hémagglutination
fr-CAFrench (CANADA)
Cytomégalovirus , Ac:Présence-Seuil:Temps ponctuel:Sérum^Donneur:Ordinal:Hémagglutination
fr-FRFrench (FRANCE)
Cytomegalovirus Ab:PrThr:Pt:Ser^Donor:Ord:HA
it-ITItalian (ITALY)
Citomegalovirus , Ab:PrThr:Pt:Siero^donatore:Ord:HA
pt-BRPortuguese (BRAZIL)
Citomegalovírus Ac:ACnc:Pt:Soro^doador:Ord:Hemaglutinação
es-ESSpanish (SPAIN)
Citomegalovirus Anticuerpos:PrThr:Punto temporal:Suero^donante:Ord:Hemaglutinacion
tr-TRTurkish (TURKEY)
Cytomegalovirus Ab:MevcEşik:Zmlı:Ser^verici:Srl:HA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47363-7