48597-9cycloSPORINE [Mass/volume] in Blood by Immunoassay --troughActive
Part Descriptions
LP16098-3 cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. [PMID:19545653]
Source: Regenstrief LOINC, PMID: 19545653
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
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Source: Wikipedia, Trough levels for therapeutic drug monitoring
Fully-Specified Name
- Component
- cycloSPORINE^trough
- Property
- MCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- cycloSPORINE Trough Bld IA-mCnc
- Display Name
- cycloSPORINE trough IA (Bld) [Mass/Vol]
- Consumer Name Alpha
- cycloSPORINE trough, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Change Reason
- The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common US Lab Results Rank
- 13314
Member of these Groups
| LG19342-1 | Cyclosporine^trough| |
Language Variants Get Info
- zh-CNChinese (China)
- 环孢菌素^波谷:
质量浓度: 时间点: 全血: 定量型: 免疫测定法 - nl-NLDutch (Netherlands)
- cyclosporine^dalspiegel:
massa/volume: moment: bloed: kwantitatief: immunoassay - et-EEEstonian (Estonia)
- Tsüklosporiin^baas:
MCnc: Pt: B: Qn: IA - fr-BEFrench (Belgium)
- Cyclosporine^Creux:
Concentration de masse: Temps ponctuel: Sang: Quantitatif: IA - fr-CAFrench (Canada)
- Cyclosporine^Creux:
Concentration de masse: Temps ponctuel: Sang: Quantitatif: IA - fr-FRFrench (France)
- Ciclosporine taux résiduel:
Masse/Volume: Ponctuel: Sang: Numérique: Immunoanalyse - el-GRGreek (Greece)
- Κυκλοσπορίνη^κατώτερα επίπεδα:
Συγκέντρωση μάζας: Χρονική στιγμή: Αίμα: Ποσοτική: IA - it-ITItalian (Italy)
- Ciclosporina^valore minimo:
MCnc: Pt: Sangue: Qn: IA - pt-BRPortuguese (Brazil)
- Ciclosporina^basal:
MCnc: Pt: SgTotal: Qn: Imunoensaio - ru-RURussian (Russian Federation)
- Циклоспорин^остаточная концентрация:
МассКонц: ТчкВрм: Кр: Колич: IA - es-MXSpanish (Mexico)
- cicloesporino ^ canal:
Concentración de masa: Punto temporal: Sangre: Cuantitativo: Inmunoensayo - es-ESSpanish (Spain)
- Ciclosporina^Valle monitorización terapéutica de fármacos:
Concentración de masa: Punto temporal: Sangre: Qn: IA - tr-TRTurkish (Turkey)
- Siklosporin^en düşük:
KütlKons: Zmlı: Kan: Kant: İA
Example Units
| Unit | Source |
|---|---|
| ug/L | Example UCUM Units |
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48597-9
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright