LOINC
Version 2.71

48800-7Second trimester quad maternal screen panel - Serum or PlasmaActive

Term Description

The Quad screen, perfomed at 16-18 weeks' gestation (second trimester) is used to assess fetal risk of Trisomy 21 (Down's syndrome), Trisomy 18 (Edward's syndrome) and Open Neural Tube defects. It has 81% sensitivity for Down syndrome detection and a false-positive rate of 7%.
Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
48800-7 Second trimester quad maternal screen panel - Serum or Plasma
Indent49087-0 Maternal screen clinical predictors panel
IndentIndent30525-0 Age R-a a
IndentIndent43993-5 Age at delivery O a
IndentIndent11778-8 Delivery date Estimated O
IndentIndent11977-6 [#] Parity O {#}
IndentIndent11996-6 [#] Pregnancies O {#}
IndentIndent21484-1 Mother's race O
IndentIndent21112-8 Birth date O {mm/dd/yyyy}
IndentIndent29463-7 Body weight O [lb_av];kg
IndentIndent32624-9 Race O
IndentIndent18185-9 Gestational age O wk
IndentIndent21299-3 Gestational age method O
IndentIndent11878-6 Number of fetuses by US O {#}
IndentIndent8665-2 Last menstrual period start date O {date}
IndentIndent34970-4 Ultrasound date O
IndentIndent33248-6 Diabetes status [Identifier] O
IndentIndent44877-9 Insulin dependent diabetes mellitus [Presence] O
IndentIndent49053-2 History of Neural tube defect Narrative O
IndentIndent68327-6 Egg donor age a
IndentIndent68328-4 Previous fetus defect
Indent1834-1 Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma O ng/mL
Indent20450-3 Alpha-1-Fetoprotein [Multiple of the median] in Serum or Plasma R {M.o.M}
Indent49585-3 Alpha-1-Fetoprotein multiple of the median cutoff [Multiple of the median] in Serum or Plasma O {M.o.M}
Indent23811-3 Alpha-1-Fetoprotein [Multiple of the median] adjusted in Serum or Plasma O {M.o.M}
Indent43998-4 Alpha-1-Fetoprotein [Multiple of the median] adjusted for diabetes in Serum or Plasma O {M.o.M}
Indent43996-8 Alpha-1-Fetoprotein [Multiple of the median] adjusted for diabetes+weight in Serum or Plasma O {M.o.M}
Indent50610-5 Alpha-1-Fetoprotein [Multiple of the median] adjusted for multiple gestations in Serum or Plasma O {M.o.M}
Indent43997-6 Alpha-1-Fetoprotein [Multiple of the median] adjusted for weight in Serum or Plasma O {M.o.M}
Indent23812-1 Alpha-1-Fetoprotein [Multiple of the median] unadjusted in Serum or Plasma O {M.o.M}
Indent19080-1 Choriogonadotropin [Units/volume] in Serum or Plasma O m[IU]/mL
Indent20465-1 Choriogonadotropin [Multiple of the median] in Serum or Plasma R {M.o.M}
Indent32166-1 Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma O {M.o.M}
Indent2250-9 Estriol (E3).unconjugated [Mass/volume] in Serum or Plasma O ng/mL
Indent20466-9 Estriol (E3).unconjugated [Multiple of the median] in Serum or Plasma R {M.o.M}
Indent21264-7 Estriol (E3).unconjugated [Multiple of the median] adjusted in Serum or Plasma O {M.o.M}
Indent21265-4 Estriol (E3).unconjugated [Multiple of the median] unadjusted in Serum or Plasma O {M.o.M}
Indent23883-2 Inhibin A [Mass/volume] in Serum or Plasma O pg/L
Indent35738-4 Inhibin A [Multiple of the median] in Serum or Plasma R {M.o.M}
Indent36904-1 Inhibin A [Multiple of the median] adjusted in Serum or Plasma O {M.o.M}
Indent36905-8 Inhibin A [Multiple of the median] unadjusted in Serum or Plasma O {M.o.M}
Indent48803-1 Neural tube defect risk [Likelihood] in Fetus R %
Indent43994-3 Trisomy 18 risk [Likelihood] in Fetus R {risk}
Indent47223-3 Fetal Trisomy 18 risk [Likelihood] Based on maternal age O {risk}
Indent49582-0 Trisomy 18 risk cutoff in Fetus O
Indent43995-0 Trisomy 21 risk [Likelihood] in Fetus R {risk}
Indent49090-4 Fetal Trisomy 21 risk [Likelihood] Based on maternal age O {risk}
Indent49583-8 Trisomy 21 risk cutoff in Fetus O
Indent49092-0 Second trimester quad maternal screen [Interpretation] in Serum or Plasma Narrative O

Fully-Specified Name

Component
Second trimester quad maternal screen panel
Property
-
Time
Pt
System
Ser/Plas
Scale
-
Method

Additional Names

Short Name
2nd trimester 4 screen Pnl SerPl
Display Name
Second trimester quad maternal screen panel
Consumer Name Alpha
Second trimester quad maternal screen panel, Blood

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.42
Order vs. Observation
Order
Common Orders Rank
83
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
49085-4 First and Second trimester integrated maternal screen panel

Language Variants Get Info

zh-CNChinese (China)
中期妊娠孕妇四项筛查组套:-:时间点:血清/血浆:-:
nl-NLDutch (Netherlands)
tweede trimester quad maternale screening panel:-:moment:serum of plasma:-:
et-EEEstonian (Estonia)
Sünnieelne kromosoomihaiguste riskihinnang II trimestril (nelja markeriga):-:Pt:S/P:-:
fr-BEFrench (Belgium)
Screening maternel. Panel quadruple test Trimestre II:-:Temps ponctuel:Sérum/Plasma:-:
fr-FRFrench (France)
Dépistage maternel au cours du 2nd trimestre grossesse quadruplet panel:-:Ponctuel:Sérum/Plasma:-:
it-ITItalian (Italy)
Secondo trimestre, panel quadruplo screening materno:-:Pt:Siero/Plasma:-:
pt-BRPortuguese (Brazil)
Triagem do segundo semestre de maternidade penta painel:-:Pt:Sor/Plas:-:
ru-RURussian (Russian Federation)
Второй триместр квад мать скрин панель:-:ТчкВрм:Сыв/Плаз:-:
es-ESSpanish (Spain)
Panel de Cribado materno cuadruple del segundo trimestre:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:-:

LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48800-7 https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/48800-7