49128-2

Rickettsia typhus group identified in Specimen by Sequencing

Active

Part Descriptions

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977.[PMID: 271968] Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost.[PMID: 18576944] Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template.[PMID: 20858600] Source: Regenstrief LOINC

LP16745-9   Rickettsia typhus group
Rickettsia is a genus of non-motile, Gram-negative, and highly pleomorphic bacteria. Their survival depends on entry, growth, and replication within the cytoplasm of eukaryotic host cells. Rickettsia species are carried by many ticks, fleas, and lice, and cause a variety of diseases in humans. Rickettsia is classified into three groups: spotted fever, typhus and scrub typhus. Original classification was based on serology and has since been confirmed by DNA sequencing.

Rickettsia typhus group and associated illnesses include R typhi (Murine typhus) and R prowazekii (epidemic, recrudescent and sporadic typhus). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Rickettsia typhus group (Wikipedia)

Fully-Specified Name

Component

Rickettsia typhus group identified

Property

Prid

Time

Pt

System

XXX

Scale

Nom

Method

Sequencing

Additional Names

Short Name

Rick Typhus Spec Seq

Display Name

R. typhus group identified Sequencing Nom (Specimen)

Consumer Name Alpha

Rickettsia typhus group test, Specimen

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.21

Last Updated

Version 2.69

Change Reason

Changed method from Amplification/Sequencing because Amplification always occurs before sequencing

Order vs. Observation

Both

Member of these Groups

Language Variants

Related Names

• high-throughput sequencing
• HTS
• ID
• Identity or presence
• Infectious Disease
• InfectiousDisease
• Isolated
• Microbiology
• Misc
• Miscellaneous
• Next generation sequencing
• NGS
• Nominal
• Other
• Point in time
• Random
• Rick Typhus
• Ricket
• Rickettsial
• Spec
• To be specified in another part of the message
• Typh
• Typhus
• Unspecified

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CodeSystem lookup

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LOINC Copyright

Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.