LOINC
Version 2.73

49244-7Alpha 1 antitrypsin phenotype [Interpretation] in Serum or Plasma NarrativeActive

Part Description

LP17187-3   Alpha 1 antitrypsin phenotype
Alpha-1 antitrypsin deficiency is a relatively common autosomal recessive condition. The most common deficiency alleles in the alpha-1-antitrypsin gene on the protease inhibitor locus are PI*Z and PI*S. The normal allele is PI*M. Patients homozygous for PI*Z or PI*S or heterozygous PI*Z/PI*S will have decreased alpha-1-antitrypsin levels, with PI*Z/PI*Z having lowest levels of 10-20% of normal. Patients with PI*Z/PI*Z or PI*S/PI*Z genotypes reportedly have increased risk of childhood liver disease and chronic obstructive pulmonary disease(COPD) and emphysema in adult life. PI*M/PI*Z patients may have decreased pulmonary function and increased risk for COPD, especially smokers. Source: Regenstrief Institute

Fully-Specified Name

Component
Alpha 1 antitrypsin phenotype
Property
Imp
Time
Pt
System
Ser/Plas
Scale
Nar
Method

Additional Names

Short Name
A1AT Phenotyp SerPl-Imp
Display Name
Alpha 1 antitrypsin phenotype Nar [Interp]
Consumer Name Alpha
Interpretation of Alpha 1 antitrypsin phenotype test result, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.73
Change Reason
Release 2.71: COMPONENT: Changed for naming consistency across LOINC.;
Order vs. Observation
Observation
Common US Lab Results Rank
6812

Member of these Groups

LG13381-5 Alpha 1 antitrypsin phenotype|Imp|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
Alpha 1 抗胰蛋白酶表现型:印象:时间点:血清/血浆:叙述型:
nl-NLDutch (Netherlands)
alfa-1-antitrypsine fenotype:interpretatie:moment:serum of plasma:tekstueel:
fr-BEFrench (Belgium)
Phénotypage de l'alpha-1-antitrypsine:Impression/interprétation d'étude:Temps ponctuel:Sérum/Plasma:Narratif:
fr-CAFrench (Canada)
Phénotype de l'alpha 1 antitrypsine:Impression/interprétation d'étude:Temps ponctuel:Sérum/Plasma:Narratif:
fr-FRFrench (France)
Alpha-1 antitrypsine phénotype:Interprétation:Ponctuel:Sérum/Plasma:Résultat textuel:
it-ITItalian (Italy)
Alfa 1 antitripsina, fenotipo:Imp:Pt:Siero/Plasma:Nar:
pt-BRPortuguese (Brazil)
Alfa 1 antitripsina Fenotipagem:Imp:Pt:Sor/Plas:Nar:
ru-RURussian (Russian Federation)
Альфа 1 антитрипсин фенотипирование:Впчт:ТчкВрм:Сыв/Плаз:Опис:
es-MXSpanish (Mexico)
Fenotipado de alfa 1 antitripsina:Impresión / interpretación del estudio:Punto temporal:Suero o Plasma:Narrativo:
es-ESSpanish (Spain)
Fenotipo Alfa 1 antitripsina:Impresión/interpretación del estudio:Punto temporal:Suero o Plasma:Narrativo:
tr-TRTurkish (Turkey)
Alfa 1 antitripsin fenotipleme:İzlnm:Zmlı:Ser/Plaz:Öykü:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49244-7