49310-6Nuclear Ab pattern [Interpretation] in Serum NarrativeActive
Part Descriptions
LP16670-9 Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
[PMID:24563360]
Source: Regenstrief LOINC
LP29188-7 Nuclear Ab pattern
Nuclear antibody patterns are distinguishable fluorescent designs that occur when autoantibodies in patient serum bind with mammalian cells that have been fixed to a glass slide. The bound autoantibodies are then coated with anti-human IgG antibodies that are tagged with a fluorochrome stain. The slide is then viewed under a fluorescent microscope where the various patterns of fluorescence can be seen depending upon what autoantibodies are present. The fluorescent patterns typically reported include nuclear, centromere, or nucleolar. The nuclear pattern is more specifically described as speckled, homogenous, or peripheral. The patterns seen are associated with the autoantibodies that are produced in certain systemic autoimmune diseases including systemic lupus erythematosus (SLE), scleroderma (SSc), polymyositis/dermatomyositis (PM/DM), and rheumatoid arthritis (RA). The autoantibodies associated with these autoimmune diseases bind with antigens that are present in all cells of the body and destroy tissue in various organs. Many of the antibodies are present in more than one disorder and in differing titers.[PMID:19277826]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Nuclear Ab pattern
- Property
- Imp
- Time
- Pt
- System
- Ser
- Scale
- Nar
- Method
Additional Names
- Short Name
- ANA Pat Ser-Imp
- Display Name
- Nuclear Ab pattern Nar (S) [Interp]
- Consumer Name Alpha
- Interpretation of Nuclear Ab pattern test result, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common US Lab Results Rank
- 6222
Member of these Groups
LG1864-0 | Nuclear Ab pattern| |
Language Variants Get Info
- zh-CNChinese (China)
- 细胞核 抗体模式:
印象: 时间点: 血清: 叙述型: - nl-NLDutch (Netherlands)
- nucleaire As-patroon:
interpretatie: moment: serum: tekstueel: - fr-BEFrench (Belgium)
- Nucléaire Anticorps.Profil des Ac:
Impression/interprétation d'étude: Temps ponctuel: Sérum: Narratif: - fr-CAFrench (Canada)
- Nucléaire , Patron des Ac:
Impression/interprétation d'étude: Temps ponctuel: Sérum: Narratif: - fr-FRFrench (France)
- Noyau anticorps aspect:
Interprétation: Ponctuel: Sérum: Résultat textuel: - de-DEGerman (Germany)
- Nukleärer Ak-Muster:
Interpretation: Zeitpunkt: Serum: Freitext: - it-ITItalian (Italy)
- Nucleare profilo Ab:
Imp: Pt: Siero: Nar: - pt-BRPortuguese (Brazil)
- Nuclear Ac padrão:
Imp: Pt: Soro: Nar: - ru-RURussian (Russian Federation)
- Ядерный Ат паттерн:
Впчт: ТчкВрм: Сыв: Опис: - es-MXSpanish (Mexico)
- Patrón de Ab nuclear:
Impresión / interpretación del estudio: Punto temporal: Suero: Narrativo: - es-ESSpanish (Spain)
- Nuclear Patrón de anticuerpos:
Impresión/interpretación del estudio: Punto temporal: Suero: Narrativo: - tr-TRTurkish (Turkey)
- Nükleer Ab yapısı:
İzlnm: Zmlı: Ser: Öykü:
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