49617-4Carbapenem resistance blaKPC gene [Presence] by Molecular methodActive
Part Description
LP64707-0 Bacterial carbapenem resistance blaKPC gene
Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Bacterial carbapenem resistance blaKPC gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- blaKPC Islt/Spm Ql
- Display Name
- Carbapenem resistance blaKPC gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha
- Carbapenem resistance blaKPC gene
Example Answer List LL360-9
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.66
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85762-3 | Blood pathogens panel by NAA with non-probe detection in Positive blood culture |
| 97324-8 | Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method |
| 85502-3 | Carbapenemase resistance genes panel by Molecular genetics method |
| 93698-9 | Gram negative bacterial resistance panel by Molecular genetics method |
| 93407-5 | Gram negative blood culture panel by NAA with probe detection in Positive blood culture |
| 97608-4 | Joint pathogens panel - Synovial fluid by NAA with non-probe detection |
| 92958-8 | Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with non-probe detection |
Language Variants Get Info
- zh-CNChinese (China)
- 细菌碳青霉烯类耐药 blaKPC 基因:
存在情况或阈值: 时间点: 分离株/标本: 序数型: 分子遗传学类实验室方法 - nl-NLDutch (Netherlands)
- bacteriële carbapenemresistentie blaKPC-gen:
aanwezigheid: moment: isolaat of monster: ordinaal: moleculair genetisch onderzoek - fr-CAFrench (Canada)
- Gène bactérien de résistance à la carbapéném blaKPC:
Présence-Seuil: Temps ponctuel: Isolat/Échantillon: Ordinal: Molgen - fr-FRFrench (France)
- Résistance bactérienne aux carbapénèmases blaKPC gène:
Présence/Seuil: Ponctuel: Isolat/échantillon: Qualitatif: Biologie moléculaire - it-ITItalian (Italy)
- Resistenza batterica ai carbapenemici, gene blaKPC:
PrThr: Pt: Isolato/Campione: Ord: Molgen - pt-BRPortuguese (Brazil)
- bla(KPC) gene:
ACnc: Pt: Isolado: Ord: Sonda com limite de detecção da amplificação de alvo - es-MXSpanish (Mexico)
- Gen blaKPC de resistencia a carbapenémicos bacterianos:
Presencia o umbral: Punto temporal: Aislado o espécimen: Ordinal: Genética molecular - es-ESSpanish (Spain)
- Gen bla(KPC):
PrThr: Punto temporal: Muestra aislada: Ord: Genética molecular
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49617-4
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LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright