LOINC
Version 2.67

49617-4Carbapenem resistance blaKPC gene [Presence] by Molecular methodActive

Part Description

LP64707-0   Bacterial carbapenem resistance blaKPC gene
Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaKPC gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
blaKPC Islt/Spm Ql
Display Name
Carbapenem resistance blaKPC gene Molgen Ql (Islt/Spec)

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.66
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
85762-3 Blood pathogens panel by NAA with non-probe detection in Positive blood culture
93698-9 Gram negative bacterial resistance panel by Molecular genetics method
93407-5 Gram negative blood culture panel by NAA with probe detection in Positive blood culture
92958-8 Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with non-probe detection

Language Variants Get Info

zh-CNChinese (CHINA)
细菌碳青霉烯类耐药 blaKPC 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (NETHERLANDS)
bacteriële carbapenemresistentie blaKPC-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
fr-CAFrench (CANADA)
Résistance bacterienne carbapénémase blaKPC gène:Présence-Seuil:Temps ponctuel:Isolat/Échantillon:Ordinal:Molgen
fr-FRFrench (FRANCE)
Résistance bactérienne aux carbapénèmases blaKPC gène:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
de-ATGerman (AUSTRIA)
Carbapenem Resistenz Gen (blaKPC) qualitativ
it-ITItalian (ITALY)
Resistenza batterica ai carbapenemici, gene blaKPC:PrThr:Pt:Isolato/Campione:Ord:Molgen
pt-BRPortuguese (BRAZIL)
bla(KPC) gene:ACnc:Pt:Isolado:Ord:Sonda com limite de detecção da amplificação de alvo
es-ESSpanish (SPAIN)
Gen bla(KPC):PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49617-4