LOINC
Version 2.73

51748-2PCA-Tr Ab [Titer] in Cerebral spinal fluidActive

Part Description

LP31709-6   Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE).[PMID:22412264] PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed.[PMID:22412264] Source: Regenstrief LOINC, Cytoplasmic

Fully-Specified Name

Component
Purkinje cell cytoplasmic type Tr Ab
Property
Titr
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
PCA-Tr Ab Titr CSF
Display Name
PCA-Tr Ab (CSF) [Titer]
Consumer Name Alpha
PCA-Tr antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.73
Change Reason
Changed "Purkinje cells" in Component to the more common name, "Purkinje cell cytoplasmic".
Order vs. Observation
Both
Common US Lab Results Rank
4875

Member of these Groups

LG20854-2 Purkinje cell cytoplasmic type Tr Ab|Titr|Pt|CSF

Language Variants Get Info

zh-CNChinese (China)
浦肯雅细胞胞浆 Tr 型 抗体:滴定度:时间点:脑脊液:定量型:
nl-NLDutch (Netherlands)
purkinjecellen type Tr As:titer:moment:liquor cerebrospinalis:kwantitatief:
fr-BEFrench (Belgium)
Cellules de Purkinje type TR Ac:Titre:Temps ponctuel:LCR:Quantitatif:
fr-CAFrench (Canada)
Cellules de Purkinje cytoplasmique type Tr , Ac:Titre:Temps ponctuel:LCR:Quantitatif:
fr-FRFrench (France)
Tr anticorps:Titre:Ponctuel:Liquide céphalorachidien:Numérique:
it-ITItalian (Italy)
Cellule di Purkinje tipo Tr Ab:Titr:Pt:LCS:Qn:
pt-BRPortuguese (Brazil)
Células Purkinje tipo Tr Ac:Título:Pt:LCR:Qn:
ru-RURussian (Russian Federation)
Пуркинье клетки тип Tr Ат:Титр:ТчкВрм:ЦСЖ:Колич:
es-MXSpanish (Mexico)
Citoplasma de células de Purkinje tipo Tr Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:
es-ESSpanish (Spain)
Células de Purkinje tipo Tr Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Qn:
tr-TRTurkish (Turkey)
Purkinje hücreleri tip Tr Ab:Titr:Zmlı:BOS:Kant:

Example Units

Unit Source
{titer} Example UCUM Units
titer REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=51748-2