LOINC
Version 2.73

5233-2Intrinsic factor Ab [Presence] in Serum by Radioimmunoassay (RIA)Active

Part Descriptions

LP15673-4   Intrinsic factor
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. Upon entry into the stomach, vitamin B12 becomes bound to one of two B12 binding proteins present in gastric juice. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, enabling it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12 -intrinsic factor complex. In pernicious anemia, an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can also cause intrinsic factor deficiency and anemia through damage to the parietal cells of the stomach wall. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, intrinsic factor (Wikipedia)

LP15673-4   Intrinsic factor
A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results in ANEMIA, PERNICIOUS. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Intrinsic factor Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
RIA

Additional Names

Short Name
IF Ab Ser Ql RIA
Display Name
Intrinsic factor Ab RIA Ql (S)
Consumer Name Alpha
Intrinsic factor antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common US Lab Results Rank
18809

Member of these Groups

LG8731-4 Intrinsic factor Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
内因子 抗体:存在情况或阈值:时间点:血清:序数型:放射免疫分析法
nl-NLDutch (Netherlands)
intrinsieke factor As:aanwezigheid:moment:serum:ordinaal:RIA
et-EEEstonian (Estonia)
Sisemine faktor antikehad:PrThr:Pt:S:Ord:RIA
fr-BEFrench (Belgium)
Facteur intrinsèque Ac:PrThr:Temps ponctuel:Sérum:Ordinal:RIA
fr-CAFrench (Canada)
Facteur intrinsèque , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:RIA
fr-FRFrench (France)
Facteur intrinsèque anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Radioimmunoanalyse
de-DEGerman (Germany)
Intrinsic Factor Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Radioimmunoassay
it-ITItalian (Italy)
Fattore intrinseco Ab:PrThr:Pt:Siero:Ord:RIA
ko-KRKorean (Korea, Republic of)
내재 인자 항체:임의농도:검사시점:혈청:순위척도:방사선면역측정법
pl-PLPolish (Poland)
czynnik wewnętrzny przeciwciało:obecność lub wartość progowa:Punkt w czasie:Surowica:Porządkowy:Metoda radioimmunologiczna
pt-BRPortuguese (Brazil)
Fator intrínseco Ac:ACnc:Pt:Soro:Ord:RIE
ru-RURussian (Russian Federation)
Внутренний фактор Ат:PrThr:ТчкВрм:Сыв:Пор:РИА
es-ARSpanish (Argentina)
[anticuerpo anti - ] factor intrínsico [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:radioinmunoensayo
es-MXSpanish (Mexico)
Factor intrínseco Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Radioinmunoensayo (RIA)
es-ESSpanish (Spain)
Factor intrínseco Anticuerpos:PrThr:Punto temporal:Suero:Ord:Radioinmunoensayo (RIA)
tr-TRTurkish (Turkey)
İntrinsik faktör Ab:MevcEşik:Zmlı:Ser:Srl:RIA

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