LOINC
Version 2.67

52750-7Activated protein C resistance [Presence] in Platelet poor plasma by Coagulation assayActive

Part Descriptions

LP18494-2   Activated protein C resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC) which increases the risk of a clotting disorder. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Source: National Library of Medicine, MeSH 2006

LP18494-2   Activated protein C resistance
Activated protein C resistance (APC) has emerged as the most frequent abnormality in patients with idiopathic thrombosis. Patients found to be heterozygous for APC resistence have a seven fold increased risk for venous thrombosis as compared to the general popualtion. Homozygous individuals have an eight fold increased risk of thrombosis. Familial studies and counselling should be considered for positive patients. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Often measured as the ratio of the Appt W APC. Source: Regenstrief Institute

Fully-Specified Name

Component
Activated protein C resistance
Property
PrThr
Time
Pt
System
PPP
Scale
Ord
Method
Coag

Additional Names

Short Name
aPCR PPP Ql
Display Name
Activated protein C resistance Coag Ql (PPP)

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.56
Change Reason
Property changed from Acnc to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
活化蛋白 C 抗性:存在情况或阈值:时间点:贫血小板血浆:序数型:凝血功能分析
nl-NLDutch (NETHERLANDS)
geactiveerd proteïne C-resistentie:aanwezigheid:moment:plaatjesarm plasma:ordinaal:stollingsmethode
et-EEEstonian (ESTONIA)
Aktiveeritud proteiini C resistentsus:PrThr:Pt:PPP:Ord:Koagulomeetria
fr-BEFrench (BELGIUM)
Résistance à la protéine C activée:PrThr:Temps ponctuel:Plasma pauvre en plaquettes:Ordinal:Test de coagulation
fr-CAFrench (CANADA)
Résistance à la protéine C activée:Présence-Seuil:Temps ponctuel:Plasma pauvre en plaquettes:Ordinal:Test de coagulation
fr-FRFrench (FRANCE)
Protéine C activée résistance:Présence/Seuil:Ponctuel:Plasma pauvre en plaquettes:Qualitatif:Coagulation
de-ATGerman (AUSTRIA)
APC-Resistenz (qual.)
de-DEGerman (GERMANY)
Aktiviertes Protein C-Resistenz:AKnz:Pkt:PPP:Ord:Koag
it-ITItalian (ITALY)
Proteina C attivata, resistenza:PrThr:Pt:PPP:Ord:Coag
pt-BRPortuguese (BRAZIL)
Resistência a proteína C ativada:ACnc:Pt:PPPQ:Ord:Coagulação
ru-RURussian (RUSSIAN FEDERATION)
Активированный протеин С резистентность:PrThr:ТчкВрм:ОПП:Пор:Коаг
es-ESSpanish (SPAIN)
Resistencia a la proteína C activada:PrThr:Punto temporal:Plasma pobre en plaquetas:Ord:Coagulativo
tr-TRTurkish (TURKEY)
Aktiflenmiş protein C resistans:MevcEşik:Zmlı:TFkP:Srl:Koag

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=52750-7