Version 2.69

52984-2Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma by ImmunoassayActive

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Cytomegalovirus Ab.IgG avidity

Additional Names

Short Name
CMV IgG Avidity SerPl IA-Rto
Display Name
CMV IgG avidity IA [Ratio]
Consumer Name Alpha
Cytomegalovirus (CMV) IgG avidity, Blood

Basic Attributes

First Released
Version 2.24
Last Updated
Version 2.64
Change Reason
Property has been changed from ACnc to reflect the fact that avidity by definition is a ratio.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser to Ser/Plas since this test can also be performed on plasma.
Order vs. Observation

Formula (Readable)

Avidity % = (absorbance of avidity CMV IgG well/absorbance of standard CMV IgG well)x100

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets

Language Variants Get Info

zh-CNChinese (China)
巨细胞病毒 抗体.IgG 亲合力:比率:时间点:血清/血浆:定量型:免疫测定法
nl-NLDutch (Netherlands)
Cytomegalovirus As.IgG-aviditeit:verhouding:moment:serum of plasma:kwantitatief:immunoassay
et-EEEstonian (Estonia)
Tsütomegaloviirus antikehad.IgG aviidsus:Suhe:Pt:S/P:Qn:IA
fr-BEFrench (Belgium)
Cytomégalovirus Anticorps.avidité des IgG:Ratios:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-CAFrench (Canada)
Cytomégalovirus , Ac.avidité des IgG:Ratios:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-FRFrench (France)
Cytomégalovirus Ac IgG avidité:Ratio:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
de-DEGerman (Germany)
Cytomegalievirus Ak.IgG-Avidität:AKnz:Pkt:Ser:Qn:EIA
it-ITItalian (Italy)
Citomegalovirus , Ab.avidità IgG:Rapporto:Pt:Siero/Plasma:Qn:IA
pt-BRPortuguese (Brazil)
Citomegalovírus Ac.IgG avidez:ACnc:Pt:Soro:Qn:Imunoensaio
ru-RURussian (Russian Federation)
Цитомегаловирус Ат.IgG авидность:Отношение:ТчкВрм:Сыв/Плаз:Колич:IA
es-ESSpanish (Spain)
Citomegalovirus Avidez IgG:Fracción:Punto temporal:Suero o Plasma:Qn:IA
tr-TRTurkish (Turkey)
Cytomegalovirus Ab.IgG avidite:Oran:Zmlı:Ser/Plaz:Kant:İA

Example Units

Unit Source
% Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info