LOINC
Version 2.67

53028-7Cyclic citrullinated peptide Ab [Presence] in SerumActive

Part Descriptions

LP29176-2   Cyclic citrullinated peptide
Citrullinated peptide (CCP) is a naturally occurring protein that is produced during the metabolism of ornithine to arginine. CCP proteins are found in synovial tissue of patients with rheumatoid arthritis (RA). High levels of antibodies to CCP have a strong association with RA and are predictive of an aggressive and destructive disease outcome. CCP antibody tests can help diagnose RA when the rheumatoid factor (RF) is negative or below 50 IU/mL.(Pagana, Kathleen Deska, and Timothy James Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. St. Louis, MO: Mosby/Elsevier, 2014. Print.) .) IgA to CCP is more elevated in patients with RA than levels found in healthy individuals or those with other rheumatic diseases. [PMID: 18565246] Source: Regenstrief LOINC

LP37859-3   Cyclic citrullinated peptide Ab
Anti-citrullinated protein/peptide antibodies (ACPAs) are autoantibodies (antibodies directed against one or more of the individual's own proteins) frequently detected in rheumatoid arthritis patients. During inflammation, citrulline is incorporated enzymatically into proteins[1], what is called citrullination. Recently, these ACPAs have turned up as powerful biomarkers, which are accepted as a major diagnostic tool in diagnosing rheumatoid arthritis (RA) already in a very early stage of disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Cyclic citrullinated peptide Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Short Name
cCP Ab Ser Ql
Display Name
Cyclic citrullinated peptide Ab Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
环瓜氨酸肽 抗体:存在情况或阈值:时间点:血清:序数型:
nl-NLDutch (NETHERLANDS)
cyclisch citrulline-peptide As:aanwezigheid:moment:serum:ordinaal:
et-EEEstonian (ESTONIA)
Tsükliline tsitrulleeritud peptiid antikehad:PrThr:Pt:S:Ord:
fr-BEFrench (BELGIUM)
Peptide citrulliné cyclique Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
fr-CAFrench (CANADA)
Peptide citrulliné cyclique , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FRFrench (FRANCE)
Peptide cyclique citrulliné anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
de-ATGerman (AUSTRIA)
CCP-AK qual.
de-DEGerman (GERMANY)
Cyclisches Citrullin-Peptid Ak:AKnz:Pkt:Ser:Ord:
el-GRGreek (GREECE)
Κυκλικό κιτρουλλινιωμένο πεπτίδιο Αντίσωμα:PrThr:Χρονική στιγμή:Ορός:Τακτική:
it-ITItalian (ITALY)
Peptide ciclico citrullinato , Ab:PrThr:Pt:Siero:Ord:
pt-BRPortuguese (BRAZIL)
Peptídeo Cíclico Citrulinado Ac:ACnc:Pt:Soro:Ord:
ru-RURussian (RUSSIAN FEDERATION)
Циклический цитруллинизированный пептид Ат:PrThr:ТчкВрм:Сыв:Пор:
es-ESSpanish (SPAIN)
Peptido cíclico citrulinado Anticuerpos:PrThr:Punto temporal:Suero:Ord:
tr-TRTurkish (TURKEY)
Siklik sitrülline peptid Ab:MevcEşik:Zmlı:Ser:Srl:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53028-7