LOINC
Version 2.73

53712-6Neuronal nuclear type 2 Ab [Titer] in Cerebral spinal fluidActive

Term Description

Antineuronal Nuclear Antibody (ANNA) Type 2 Cerebrospinal Fluid (CSF) Titer. This antibody recognizes a set of protein antigens of 55 and 80 kD found in neuronal cell nuclei. Patients usually present with signs of midbrain, brain stem, cerebellar and/or spinal cord dysfunction. Ocular opsoclonus-myoclonus may be a symptom. Para neoplastic opsoclonus, which is characterized by involuntary rapid movement of the eyes in both vertical and horizontal planes, is most often associated with breast cancer and SCLC (small lung cell carcinoma). The autoantibody has also been detected in patients with bladder and cervical cancer. Paraneoplastic syndromes are autoantibody-mediated neurologic disorders associated with underlying tumors. These syndromes arise when systemic tumors express antigens normally found only in neural tissues. Information from http://www.clinlabnavigator.com accessed 2008 14 02.
Source: Regenstrief LOINC

Part Descriptions

LP14164-5   Neuronal nuclear type 2
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable. Source: ARUP Laboratories, ANNA

LP39195-0   Neuronal nuclear type 2 Ab
Neuronal nuclear antibody is a neuronal paraneoplastic antibody that has been associated with cerebellar degeneration in breast, small cell lung carcinoma and gynecological cancers. Source: University of Birmingham, Neuronal antibodies

Fully-Specified Name

Component
Neuronal nuclear type 2 Ab
Property
Titr
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
Hu2 Ab Titr CSF
Display Name
Neuronal nuclear type 2 Ab (CSF) [Titer]
Consumer Name Alpha
Neuronal nuclear type 2 antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.32
Order vs. Observation
Both

Member of these Groups

LG8744-7 Neuronal nuclear type 2 Ab|Titr|Pt|CSF

Language Variants Get Info

zh-CNChinese (China)
神经元细胞核 2 型 抗体:滴定度:时间点:脑脊液:定量型:
nl-NLDutch (Netherlands)
neuronaal nucleair type 2 As:titer:moment:liquor cerebrospinalis:kwantitatief:
fr-BEFrench (Belgium)
Neuronal nucléaire de type 2 Ac:Titre:Temps ponctuel:LCR:Quantitatif:
fr-CAFrench (Canada)
Neuronal nucléaire de type 2 , Ac:Titre:Temps ponctuel:LCR:Quantitatif:
fr-FRFrench (France)
Hu2 anticorps:Titre:Ponctuel:Liquide céphalorachidien:Numérique:
it-ITItalian (Italy)
Nucleare neuronale tipo 2 Ab:Titr:Pt:LCS:Qn:
pt-BRPortuguese (Brazil)
Neuronal nuclear tipo 2 Ac:Título:Pt:LCR:Qn:
ru-RURussian (Russian Federation)
Нейрональный ядерный тип 2 Ат:Титр:ТчкВрм:ЦСЖ:Колич:
es-MXSpanish (Mexico)
Nuclear neuronal tipo 2 Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:
es-ESSpanish (Spain)
Anticuerpos Antineuronal nuclear tipo 2 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Qn:
tr-TRTurkish (Turkey)
Nöronal nükleer tip 2 Ab:Titr:Zmlı:BOS:Kant:

Example Units

Unit Source
{titer} Example UCUM Units
titer REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53712-6