LOINC
Version 2.73

56539-0Intrinsic factor Ab [Units/volume] in Serum by ImmunoassayActive

Part Descriptions

LP15673-4   Intrinsic factor
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. Upon entry into the stomach, vitamin B12 becomes bound to one of two B12 binding proteins present in gastric juice. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, enabling it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12 -intrinsic factor complex. In pernicious anemia, an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can also cause intrinsic factor deficiency and anemia through damage to the parietal cells of the stomach wall. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, intrinsic factor (Wikipedia)

LP15673-4   Intrinsic factor
A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results in ANEMIA, PERNICIOUS. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Intrinsic factor Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
IF Ab Ser IA-aCnc
Display Name
Intrinsic factor Ab IA Qn (S)
Consumer Name Alpha
Intrinsic factor antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.69
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG351-3 Intrinsic factor Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
内因子 抗体:任意型浓度:时间点:血清:定量型:免疫测定法
nl-NLDutch (Netherlands)
intrinsieke factor As:eenheid/volume:moment:serum:kwantitatief:immunoassay
et-EEEstonian (Estonia)
Sisemine faktor antikehad:Acnc:Pt:S:Qn:IA
fr-BEFrench (Belgium)
Facteur intrinsèque Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-CAFrench (Canada)
Facteur intrinsèque , Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FRFrench (France)
Facteur intrinsèque anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
it-ITItalian (Italy)
Fattore intrinseco Ab:ACnc:Pt:Siero:Qn:IA
pl-PLPolish (Poland)
czynnik wewnętrzny przeciwciało:Stężenie umowne:Punkt w czasie:Surowica:ilościowy:metoda immunochemiczna
pt-BRPortuguese (Brazil)
Fator intrínseco Ac:#N/A:Pt:Soro:Qn:Imunoensaio
ru-RURussian (Russian Federation)
Внутренний фактор Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA
es-MXSpanish (Mexico)
Factor intrínseco Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
es-ESSpanish (Spain)
Factor intrínseco Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA
tr-TRTurkish (Turkey)
İntrinsik faktör Ab:SçKons:Zmlı:Ser:Kant:İA

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

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