LOINC
Version 2.73

56724-8Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by ImmunoblotActive

Part Description

LP16760-8   Sjogrens syndrome-A extractable nuclear
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. [PMID:27184054] Source: Regenstrief LOINC, PMID: 27184054

Fully-Specified Name

Component
Sjogrens syndrome-A extractable nuclear Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IB

Additional Names

Short Name
ENA SS-A Ab Ser Ql IB
Display Name
Sjogrens syndrome-A extractable nuclear Ab IB Ql (S)
Consumer Name Alpha
Sjogrens syndrome-A extractable nuclear antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.58
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG5157-5 Sjogrens syndrome-A extractable nuclear Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
Sjogrens 综合征-a 可提取性核 抗体:存在情况或阈值:时间点:血清:序数型:免疫印迹法
nl-NLDutch (Netherlands)
SS-A extraheerbare nucleaire As:aanwezigheid:moment:serum:ordinaal:immunoblotting
fr-BEFrench (Belgium)
Syndrome de Sjögren-a nucléaire soluble Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-CAFrench (Canada)
Syndrome de Sjögren-a nucléaire soluble , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FRFrench (France)
SSA/Ro anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
it-ITItalian (Italy)
Sjogren, sindrome-nucleare estraibile A Ab:PrThr:Pt:Siero:Ord:IB
pt-BRPortuguese (Brazil)
SS-A Ac:#N/A:Pt:Soro:Ord:Imunoblot
ru-RURussian (Russian Federation)
Шегрена синдром-A экстрагируемый ядерный Ат:PrThr:ТчкВрм:Сыв:Пор:ИБ
es-MXSpanish (Mexico)
Síndrome de Sjogrens:Ab nuclear extraíble:Presencia o umbral:Punto temporal:Suero:Ordinal
es-ESSpanish (Spain)
Antígeno nuclear extraíble Síndrome de Sjogren-A (SS-A) Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
tr-TRTurkish (Turkey)
Sjögrens sendromu-A özütlenebilir nükleer Ab:MevcEşik:Zmlı:Ser:Srl:IB

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=56724-8