Version 2.74

Part Descriptions

LP14377-3   Aldosterone
Aldosterone is a steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone also stimulates H+ secretion by intercalated cells in the collecting duct, regulating plasma bicarbonate (HCO3-) levels and its acidbase balance. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Aldosterone (Wikipedia)

LP14377-3   Aldosterone
Used to detect hyper and hypo aldosteronisnm. Hypoaldosteronism can occur in any condition that causes destruction or dysfunction of the adrenal gland.1,2,4 Hypoaldosterism can be due to primary adrenal insufficiency , congenital adrenal hypoplasia, acquired secondary aldosterone deficiency (hyporeninemic hypoaldosteronism), and acquired Hyporeninemic hypoaldosteronism is the most common form of isolated hypoaldosteronism and is results from impaired renin release from the kidney. Congenital hypoaldosteronism caused by inherited enzymatic defects in aldosterone biosynthesis are rare. Corticosterone methyloxidase I (CMO I) deficiency is associated with elevated serum levels of corticosterone and low levels of 18-hydroxy-corticosterone and aldosterone. Corticosterone methyloxidase II (CMO II) deficiency produces high levels of 18-hydroxy-corticosterone, the immediate precursor of aldosterone.
Acquired primary hypoaldosteronism can be caused by the administration of heparin. Also, persistently hypotensive, critically ill patients with sepsis, pneumonia, peritonitis, cholangitis, and liver failure can have inappropriately low plasma aldosterone concentrations in relation to elevated plasma renin activity. Primary hyperaldosteronism, also referred to as Conn syndrome, is due to overproduction of aldosterone by one or both of the adrenal glands. Some recent studies suggest that 10% to 15% of Hyper thyroidism cases are due to (or associated with ) primary hyperaldosteronism. Secondary hyperaldosteronism is relatively common and can occur as the result of any condition that decreases blood flow to the kidneys (ie, renal artery stenosis), decreases blood pressure, or lowers plasma sodium levels. Secondary hyperaldosteronism may also be seen with cirrhosis, congestive heart failure. and toxemia of pregnancy. Several studies have suggested that high-normal aldosterone levels predict development of high blood pressure in normotensive subjects and that increased aldosterone action contributes to hypertension, cardiovascular fibrosis, and cardiac hypertrophy. Source: Regenstrief Institute

Fully-Specified Name

Aldosterone^3H post 25 mg captopril PO

Additional Names

Short Name
Aldost 3h p 25 mg Cpl PO SerPl-mCnc
Display Name
Aldosterone 3 Hr post 25 mg captopril PO [Mass/Vol]
Consumer Name Alpha
Aldosterone 3 hr after 25 mg Captopril by mouth, Blood

Basic Attributes

First Released
Version 2.29
Last Updated
Version 2.70
Order vs. Observation

Member of these Groups

LOINC Group Group Name
LG50487-4 Aldosterone^3H post 25 mg captopril PO|Pt|Ser/Plas

Language Variants

Tag Language Translation
zh-CN Chinese (China) 醛固酮^在口服25 mg卡托普利之后3小时:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 3Hr之后于25 mg 卡托普利 PO;3小时之后于口服25 mg卡托普利;3小时之后于口服25毫克卡托普利;在25 mg 卡托普利 PO之后3Hr;在口服25毫克卡托普利之后3小时 XXX刺激 - 在...之后 之后于... 之后于25 mg 卡托普利 PO;之后于口服25 mg卡托普利;之后于口服25毫克卡托普利;在25 mg 卡托普利 PO之后;在口服25毫克卡托普利之后 卡普多普瑞尔;圣瑞恩卡托普利;巯甲丙脯氨酸的商品名;巯甲丙脯酸;开搏通;甲丙酰膊;甲巯丙脯氨酸;甲巯丙脯酸 口服 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆 醛基甾酮;醛甾酮;醛皮质酮;醛类脂醇
fr-CA French (Canada) Aldostérone^3 h post 25 mg captopril PO:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
pt-BR Portuguese (Brazil) Aldosterona^3 hs após 25 mg captopril VO:#N/A:Pt:Sor/Plas:Qn:
Synonyms: c246; Aldost; 3H p 25 mg Cpl PO; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Oral; PST; After; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
es-ES Spanish (Spain) Aldosterona^3H pos 25 mg de captopril VO:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
it-IT Italian (Italy) Aldosterone^3h post 25 mg captopril per os:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: 3 ore dopo 25 mg di captopril per os Concentrazione di Massa dopo 25 mg di captopril per os Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione
fr-FR French (France) Aldostérone T03h après captopril (25mg,PO):Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
tr-TR Turkish (Turkey) Aldosteron^3Sa snr 25 mg kaptopril oral:KütlKons:Zmlı:Ser/Plaz:Kant:
ru-RU Russian (Russian Federation) Альдостерон^3 часа после дозы 25 мг каптоприла через рот:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
nl-NL Dutch (Netherlands) aldosteron^180 min na 25 mg captopril PO:massa/volume:moment:serum of plasma:kwantitatief:
Synonyms: 3 uur na 25 mg captopril PO
fr-BE French (Belgium) Aldostérone^3 h post 25 mg captopril PO:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
es-MX Spanish (Mexico) Aldosterona ^3 horas después de 25 mg de captopril VO:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR®

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