LOINC
Version 2.66

59069-5Nuclear Ab [Presence] in Serum by Hep2 substrateActive

Component
Nuclear Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Hep2 substrate

Additional Names

Short Name
ANA Ser Ql HEp2 subst
Display Name Beta
Nuclear Ab Hep2 substrate Ql (S)
Consumer Name Alpha
Nuclear Antibody, Blood

Part Descriptions

LP16670-9   Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
[PMID: 24563360] Source: Regenstrief LOINC

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs), also known as anti-nuclear factor or ANF, are auto-antibodies directed against contents of the cell nucleus. They are present in low numbers in the general population but higher than normal amounts in autoimmune diseases, including lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, scleroderma, and autoimmune hepatitis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Anti-nuclear antibodies

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are autoantibodies directed against contents of the cell nucleus. They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.

The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as[citation needed] Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG4652-6 Nuclear Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
细胞核 抗体:存在情况或阈值:时间点:血清:序数型:Hep2 细胞底物法
nl-NLDutch (Netherlands)
nucleaire As:aanwezigheid:moment:serum:ordinaal:hep2-substraat
et-EEEstonian (Estonia)
Tuumavastased antikehad:PrThr:Pt:S:Ord:Hep2 substraat
fr-BEFrench (Belgium)
Nucléaire Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Substrat d'Hep2
fr-CAFrench (Canada)
Nucléaire , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Substrat d'Hep2
fr-FRFrench (France)
Nuclear Ab:PrThr:Pt:Ser:Ord:Hep2 substrate
it-ITItalian (Italy)
Nucleare , Ab:PrThr:Pt:Siero:Ord:Hep2 substrato
pt-BRPortuguese (Brazil)
es-ESSpanish (Spain)
Nuclear Anticuerpos:PrThr:Punto temporal:Suero:Ord:Sustrato Hep2
tr-TRTurkish (Turkey)
Nükleer Ab:MevcEşik:Zmlı:Ser:Srl:Hep2 substrat

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59069-5