LOINC
Version 2.73

59313-7Ramelteon M-II [Mass/volume] in BloodActive

Part Description

LP100046-4   Ramelteon M-II
The major metabolite of ramelteon, M-II, is active and has approximately one tenth and one fifth the binding affinity of the parent molecule for the human MT1 and MT2 receptors, respectively, and is 17 - 25-fold less potent than ramelteon in in vitro functional assays. Although the potency of M-II at MT1 and MT2 receptors is lower than the parent drug, M-II circulates at higher concentrations than the parent producing 20 - 100 fold greater mean systemic exposure when compared to ramelteon. M-II has weak affinity for the serotonin 5-HT2B receptor, but no appreciable affinity for other receptors or enzymes. Similar to ramelteon, M-II does not interfere with the activity of a number of endogenous enzymes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ramelteon M-II

Fully-Specified Name

Component
Ramelteon M-II
Property
MCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
Ramelteon M-II Bld-mCnc
Display Name
Ramelteon M-II (Bld) [Mass/Vol]
Consumer Name Alpha
Ramelteon M-II, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Groups

LG24767-2 Ramelteon M-II|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
雷美替胺 M-II:质量浓度:时间点:全血:定量型:
nl-NLDutch (Netherlands)
ramelteon M-II:massa/volume:moment:bloed:kwantitatief:
et-EEEstonian (Estonia)
Ramelteoon M2:MCnc:Pt:B:Qn:
fr-BEFrench (Belgium)
Ramelteon M-II:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-CAFrench (Canada)
Ramelteon M-II:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FRFrench (France)
Rameltéon M-II:Masse/Volume:Ponctuel:Sang:Numérique:
it-ITItalian (Italy)
Ramelteon M-II:MCnc:Pt:Sangue:Qn:
pt-BRPortuguese (Brazil)
Ramelteon M-II::Pt:SgTotal:Qn:
ru-RURussian (Russian Federation)
Рамелтеон M-II:МассКонц:ТчкВрм:Кр:Колич:
es-MXSpanish (Mexico)
Ramelteon M-II:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
es-ESSpanish (Spain)
Ramelteon M-II:Concentración de masa:Punto temporal:Sangre:Qn:
tr-TRTurkish (Turkey)
Ramelteon M-II:KütlKons:Zmlı:Kan:Kant:

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59313-7