LOINC
Version 2.73

63249-7Ganglioside GM2 IgG+IgM Ab [Presence] in Serum by ImmunoassayActive

Part Descriptions

LP62853-4   Ganglioside GM2
Gangliosides are present in the cell membrane and are found predominantly in the nervous system. Ganglioside antibodies against different gangliosides have been associated with different conditions. The GM2 ganglioside, also called Tay-Sachs ganglioside, is a minor component of adult nervous tissue, and pathological storage of GM2 in neurons leads to motor neuron disease. Anti-GM2 IgM antibodies have been found in patients with Guillain-Barré syndrome that is associated with CMV infection. Anti-GM2 antibodies have also been associated with an acute inflammatory neuropathy as a potentially paraneoplastic phenomenon. [PMID:23341581] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, PMID: 23341581

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ganglioside GM2 Ab.IgG+IgM
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
GM2 Gangl IgG+IgM Ser Ql IA
Display Name
Ganglioside GM2 IgG+IgM IA Ql (S)
Consumer Name Alpha
Ganglioside GM2 IgG+IgM, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common US Lab Results Rank
13890

Member of these Panels

LOINC Long Common Name
82455-7 Ganglioside Ab panel - Serum

Member of these Groups

LG26352-1 Ganglioside GM2 Ab.IgG+IgM|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
神经节苷脂 GM2 抗体.IgG+IgM:存在情况或阈值:时间点:血清:序数型:免疫测定法
nl-NLDutch (Netherlands)
ganglioside GM2 As.IgG + IgM:aanwezigheid:moment:serum:ordinaal:immunoassay
et-EEEstonian (Estonia)
Gangliosiid GM2 antikehad.IgG+IgM:PrThr:Pt:S:Ord:IA
fr-BEFrench (Belgium)
Ganglioside GM2 Anticorps.IgG+IgM:PrThr:Temps ponctuel:Sérum:Ordinal:IA
fr-CAFrench (Canada)
Ganglioside GM2 , IgG+IgM:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FRFrench (France)
Ganglioside GM2 anticorps IgG+IgM:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
it-ITItalian (Italy)
Ganglioside GM2 Ab.IgG+IgM:PrThr:Pt:Siero:Ord:IA
ru-RURussian (Russian Federation)
Ганглиозид GM2 Ат.IgG+IgM:PrThr:ТчкВрм:Сыв:Пор:IA
es-MXSpanish (Mexico)
Gangliósido GM2 Ab.IgG + IgM:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
es-ESSpanish (Spain)
Gangliósido GM2 IgG+IgM:PrThr:Punto temporal:Suero:Ord:IA
tr-TRTurkish (Turkey)
Gangliozid GM2 Ab.IgG+IgM:MevcEşik:Zmlı:Ser:Srl:İA

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