LOINC
Version 2.73

63264-6Histone Ab [Presence] in Cerebral spinal fluid by ImmunoassayActive

Part Description

LP16714-5   Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. [PMID:24649358] Source: Regenstrief LOINC, PMID: 24649358

Fully-Specified Name

Component
Histone Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IA

Additional Names

Short Name
Histone Ab CSF Ql IA
Display Name
Histone Ab IA Ql (CSF)
Consumer Name Alpha
Histone antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG26116-0 Histone Ab|PrThr|Pt|CSF

Language Variants Get Info

zh-CNChinese (China)
组蛋白 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫测定法
nl-NLDutch (Netherlands)
histon As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoassay
et-EEEstonian (Estonia)
Histoon antikehad:PrThr:Pt:CSF:Ord:IA
fr-BEFrench (Belgium)
Histone Ac:PrThr:Temps ponctuel:LCR:Ordinal:IA
fr-CAFrench (Canada)
Histone , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:IA
fr-FRFrench (France)
Histones anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoanalyse
it-ITItalian (Italy)
Istone Ab:PrThr:Pt:LCS:Ord:IA
ru-RURussian (Russian Federation)
Гистон Ат:PrThr:ТчкВрм:ЦСЖ:Пор:IA
es-MXSpanish (Mexico)
Histona Ab:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunoensayo
es-ESSpanish (Spain)
Histona Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:IA
tr-TRTurkish (Turkey)
Histon Ab:MevcEşik:Zmlı:BOS:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63264-6