LOINC
Version 2.67

63420-4Gliadin peptide+tissue transglutaminase IgA+IgG Ab [Presence] in Serum by ImmunoassayActive

Part Description

LP113725-8   Gliadin peptide+tissue transglutaminase
The presence of antibodies to gliadin peptide and tissue transglutaminase can be used in conjunction with clinical findings and other lab tests to aid in the diagnosis of IgA sufficient and IgA deficient celiac disease.

Antibodies to deamidated gliadin peptide and tissue transglutaminase are specific to Celiac Disease while antibodies to gliadin are present in patients with and without gastrointestinal manifestations and are serological evidence of gluten sensitivity.

The screening starts with testing for IgA and IgG antibodies to deamidated gliadin peptide (DGP) and tissue transglutaminase (tTG) that allows for simultaneous detection for all four types of antibodies in one test (tTG/DGP screen). This step will aid in the diagnosis of gluten-sensitive enteropathies including celiac disease. Antibodies to DGP and tTG are highly specific and sensitive for those conditions When the result is positive, testing stops. When result is negative, testing will reflex to a second step. Source: LOINC partner 1

Fully-Specified Name

Component
Gliadin peptide+Tissue transglutaminase Ab.IgA+IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
Gliadin peptide+tTG IgA+IgG Ser Ql IA
Display Name
Gliadin peptide+tissue transglutaminase IgA+IgG IA Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
麦醇溶蛋白肽+组织谷氨酰胺转移酶 抗体.IgA+IgG:存在情况或阈值:时间点:血清:序数型:免疫测定法
nl-NLDutch (NETHERLANDS)
gliadinepeptide + tissue transglutaminase As.IgA + IgG:aanwezigheid:moment:serum:ordinaal:immunoassay
et-EEEstonian (ESTONIA)
Gliadiin + koe transglutaminaas Antikehad.IgA+IgG:PrThr:Pt:S:Ord:IA
fr-BEFrench (BELGIUM)
Gliadine peptidique+Transglutaminase de tissu Anticorps. IgA+IgG:PrThr:Temps ponctuel:Sérum:Ordinal:IA
fr-CAFrench (CANADA)
Toxine 1 du syndrôme du choc toxique de Staphylococcus aureus , IgA+IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FRFrench (FRANCE)
Gliadine peptide+transglutaminase tissulaire anticorps IgA+IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
it-ITItalian (ITALY)
Peptide della gliadina+Transglutaminasi tissutale , Ab.IgA+IgG:PrThr:Pt:Siero:Ord:IA
ru-RURussian (RUSSIAN FEDERATION)
Глиадин пептид+тканевая трансглутаминаза Ат.IgA+IgG:PrThr:ТчкВрм:Сыв:Пор:IA
es-ESSpanish (SPAIN)
Gliadina+transglutaminasa tisular IgA+IgG:PrThr:Punto temporal:Suero:Ord:IA
tr-TRTurkish (TURKEY)
Gliadin peptid+doku transglutaminaz Ab.IgA+IgG:MevcEşik:Zmlı:Ser:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63420-4