LOINC
Version 2.73

6788-4Kappa light chains/Lambda light chains [Mass Ratio] in Serum by ImmunoassayActive

Part Description

LP15030-7   Immunoglobulin light chains.kappa
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. [PMID:6802926] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC

Fully-Specified Name

Component
Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda
Property
MRto
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
Kappa LC/Lambda Ser IA
Display Name
Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda IA (S) [Mass ratio]
Consumer Name Alpha
Immunoglobulin light chains.kappa/Immunoglobulin Light Chains.lambda, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0h(2)
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016. Changed the LCN from 'Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda' to ' Kappa light chains/Lambda light chains' for readability.
Order vs. Observation
Observation
Common US Lab Results Rank
3908

Member of these Panels

LOINC Long Common Name
44793-8 Immunoglobulin light chains panel [Mass/volume] - Serum

Member of these Groups

LG3250-0 Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda|MRto|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
免疫球蛋白轻链.Kappa 型/免疫球蛋白轻链.Lambda:质量比率:时间点:血清:定量型:免疫测定法
nl-NLDutch (Netherlands)
immunoglobuline lichte ketens.kappa/lichte-keten immunoglobuline.lambda:massaverhouding:moment:serum:kwantitatief:immunoassay
et-EEEstonian (Estonia)
Immuunoglobuliini kerged ahelad.kapa/immuunoglobuliini kerged ahelad.lambda:MRto:Pt:S:Qn:IA
fr-BEFrench (Belgium)
Chaînes légères immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda:Ratio de masse:Temps ponctuel:Sérum:Quantitatif:IA
fr-CAFrench (Canada)
Chaînes légères d'immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda:Ratio de masse:Temps ponctuel:Sérum:Quantitatif:IA
fr-FRFrench (France)
Immunoglobuline chaines légères kappa/lambda:Masse ratio:Ponctuel:Sérum:Numérique:Immunoanalyse
it-ITItalian (Italy)
Immunoglobuline, catene leggere.kappa/Immunoglobuline, catene leggere.lambda:MRto:Pt:Siero:Qn:IA
ko-KRKorean (Korea, Republic of)
카파면역글로불린 경쇄/람다면역글로불린 경쇄:질량농도비:검사시점:혈청:정량:효소면역측정법
pt-BRPortuguese (Brazil)
Imunoglobulinas cadeias leves.kappa/Imunoglobulinas cadeias leves.lambda:MCrto:Pt:Soro:Qn:Imunoensaio
ru-RURussian (Russian Federation)
Иммуноглобулин легкие цепи.каппа/Иммуноглобулин легкие цепи.лямбда:МассОтн:ТчкВрм:Сыв:Колич:IA
es-ARSpanish (Argentina)
cadenas livianas de inmunoglobulina.kappa/cadenas livianas de inmunoglobulina.lambda:relación de concentración de masa:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-MXSpanish (Mexico)
Cadenas ligeras de inmunoglobulina kappa / Cadenas ligeras de inmunoglobulina lambda:Relación de masa:Punto temporal:Suero:Cuantitativo:Inmunoensayo
es-ESSpanish (Spain)
Cadenas ligeras de las inmunoglobulinas.kappa/Cadenas ligeras de inmunoglobulina (cadenas lambda):Relacion de Masa:Punto temporal:Suero:Qn:IA
tr-TRTurkish (Turkey)
İmmünglobulin hafif zincirler.kappa/İmmünglobulin hafif zincirler.lambda:KütlOr:Zmlı:Ser:Kant:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=6788-4