LOINC
Version 2.72

68993-5Human RNase P RNA [Presence] in Specimen by NAA with probe detectionActive

Term Description

Used as a control for determination of adequate human cells in clinical samples for viral testing
Source: Regenstrief LOINC

Part Description

LP135667-6   Human RNase P
Ribonuclease P (EC 3.1.26.5, RNase P) is a type of ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme - a ribonucleic acid that acts as a catalyst in the same way that a protein based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Further, RNase P is one of two known multiple turnover ribozymes in nature (the other being the ribosome), the discovery of which earned Sidney Altman and Thomas Cech the Nobel Prize in Chemistry in 1989: in the 1970s, Altman discovered the existence of precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA. Recent findings also reveal that RNase P has a new function. It has been shown that human nuclear RNase P is required for the normal and efficient transcription of various small noncoding RNAs, such as tRNA, 5S rRNA, SRP RNA and U6 snRNA genes., which are transcribed by RNA polymerase III, one of three major nuclear RNA polymerases in human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Human RNase P RNA
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
Human RNase P RNA Spec Ql NAA+probe
Display Name
Human RNase P RNA NAA+probe Ql (Specimen)
Consumer Name Alpha
Human RNase P, Specimen

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.69
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory specimen by NAA with probe detection

Language Variants Get Info

zh-CNChinese (China)
人核糖核酸酶 P RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
Humaan Rnase P RNA:aanwezigheid:moment:XXX:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (France)
Ribonucléase P ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
de-DEGerman (Germany)
Humane RNase P RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
it-ITItalian (Italy)
Rnasi P umana RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar
ru-RURussian (Russian Federation)
Человеческая РНКаза P РНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш
es-MXSpanish (Mexico)
ARN Rnasa P humana:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ESSpanish (Spain)
Rnase P humana RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Human Rnaz P RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=68993-5