LOINC
Version 2.73

6926-0Ganglioside GM1 IgM Ab [Titer] in SerumActive

Part Descriptions

LP36423-9   Ganglioside GM1
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. [PMID:21214559] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, PMID: 2121455

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ganglioside GM1 Ab.IgM
Property
Titr
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
GM1 Gangl IgM Titr Ser
Display Name
Ganglioside GM1 IgM (S) [Titer]
Consumer Name Alpha
Ganglioside GM1 IgM antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0h(2)
Last Updated
Version 2.73
Order vs. Observation
Observation
Common US Lab Results Rank
12881

Member of these Groups

LG17145-0 Ganglioside GM1 Ab.IgM|Titr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
神经节苷脂 GM1 抗体.IgM:滴定度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
ganglioside GM1 As.IgM:titer:moment:serum:kwantitatief:
et-EEEstonian (Estonia)
Gangliosiid GM1 antikehad.IgM:Titr:Pt:S:Qn:
fr-BEFrench (Belgium)
Ganglioside GM1 Anticorps. IgM:Titre:Temps ponctuel:Sérum:Quantitatif:
fr-CAFrench (Canada)
Ganglioside GM1 , IgM:Titre:Temps ponctuel:Sérum:Quantitatif:
fr-FRFrench (France)
Ganglioside GM1 anticorps IgM:Titre:Ponctuel:Sérum:Numérique:
it-ITItalian (Italy)
Ganglioside GM1 Ab.IgM:Titr:Pt:Siero:Qn:
ko-KRKorean (Korea, Republic of)
Monosialoganglioside GM1 Antibody.immunoglobulin M:역가:검사시점:혈청:정량:
pt-BRPortuguese (Brazil)
Monosialogangliosídeo GM1 Ac.IgM:Título:Pt:Soro:Qn:
ru-RURussian (Russian Federation)
Ганглиозид GM1 Ат.IgM:Титр:ТчкВрм:Сыв:Колич:
es-ARSpanish (Argentina)
[anticuerpo anti - ] monosialogangliósido GM1 [Ac].IgM [Inmunoglobulina M]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:
es-MXSpanish (Mexico)
Gangliósido GM1 Ab.IgM:Título:Punto temporal:Suero:Cuantitativo:
es-ESSpanish (Spain)
Gangliósido GM1 IgM:Titulo / Factor de dilución:Punto temporal:Suero:Qn:
tr-TRTurkish (Turkey)
Gangliozid GM1 Ab.IgM:Titr:Zmlı:Ser:Kant:

Example Units

Unit Source
{titer} Example UCUM Units
titer REGENSTRIEF

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