6970-8
Purkinje cells Ab [Titer] in Serum
Active
Part Descriptions
LP17260-8 Purkinje cells
Purkinje cells (or Purkinje neurons) are a class of GABAergic neuron located in the cerebellar cortex.
These cells are some of the largest neurons in the human brain, with an intricately elaborate dendritic arbor, characterized by a large number of dendritic spines. Purkinje cells are found within the Purkinje layer in the cerebellum. Purkinje cells are aligned like dominos stacked one in front of the other. Their large dendritic arbors form nearly two dimensional layers through which parallel fibers from the deeper-layer granule cells pass. These parallel fibers make relatively weaker excitatory (glutamatergic) synapses to spines in the Purkinje cell dendrite, whereas climbing fibers originating from the inferior olivary nucleus in the medulla provide very powerful excitatory input to the proximal dendrites and cell soma.
In humans, Purkinje cells are affected in a variety of diseases ranging from toxic exposure (alcohol, lithium), to autoimmune diseases and to genetic mutations (spinocerebellar ataxias, Unverricht-Lundborg disease, autism) and neurodegenerative diseases that are not thought to have a known genetic basis (cerebellar type of multiple system atrophy, sporadic ataxias).
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Source: Wikipedia, Purkinje cells (Wikipedia)
LP17260-8 Purkinje cells
The output neurons of the cerebellar cortex.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Purkinje cells Ab
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- Purkinje Cells Ab Titr Ser
- Display Name
- Purkinje cells Ab (S) [Titer]
- Consumer Name Alpha
- Purkinje cells antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank
- 11918
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 43104-9 | Paraneoplastic Ab panel - Serum |
Member of these Groups
| LOINC Group | Group Name |
|---|---|
| LG20837-7 | Purkinje cells Ab| |
Language Variants
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 浦肯雅细胞 抗体: Synonyms: |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] células de Purkinje [Ac]: |
| fr-CA | French (Canada) | Cellules de Purkinje , Ac: |
| et-EE | Estonian (Estonia) | Purkinje rakkude vastased antikehad: Synonyms: |
| pt-BR | Portuguese (Brazil) | Células Purkinje Ac: Synonyms: |
| es-ES | Spanish (Spain) | Células de Purkinje Anticuerpos: |
| ko-KR | Korean (Korea, Republic Of) | 심장전도근육 세포 항체: |
| it-IT | Italian (Italy) | Cellule di Purkinje Ab: Synonyms: |
| fr-FR | French (France) | YO anticorps: |
| tr-TR | Turkish (Turkey) | Purkinje hücreleri Ab: Synonyms: |
| ru-RU | Russian (Russian Federation) | Пуркинье клетки Ат: Synonyms: |
| nl-NL | Dutch (Netherlands) | purkinjecellen As: Synonyms: |
| fr-BE | French (Belgium) | Cellules de Purkinje Ac: Synonyms: |
| es-MX | Spanish (Mexico) | Células de Purkinje Ab: |
Example Units
| Unit | Source |
|---|---|
| titer | REGENSTRIEF |
| {titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR®
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- CodeSystem lookup
- https:
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