LOINC
Version 2.72

69930-6Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by ImmunoassayActive

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, IgM

Fully-Specified Name

Component
Varicella zoster virus Ab.IgM
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IA

Additional Names

Short Name
VZV IgM CSF Ql IA
Display Name
VZV IgM IA Ql (CSF)
Consumer Name Alpha
Varicella zoster virus (VZV; Chickenpox) IgM antibody, Spinal fluid

Example Answer List LL2010-8

Source: Estonian Society of Laboratory Medicine

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.68
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG32750-8 Varicella zoster virus

Language Variants Get Info

zh-CNChinese (China)
水痘带状疱疹病毒 抗体.IgM:存在情况或阈值:时间点:脑脊液:序数型:免疫测定法
nl-NLDutch (Netherlands)
varicella-zostervirus As.IgM:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoassay
et-EEEstonian (Estonia)
Tuulerõugeviirus antikehad.IgM:PrThr:Pt:CSF:Ord:IA
fr-BEFrench (Belgium)
Virus varicelle-zona Anticorps. IgM:PrThr:Temps ponctuel:LCR:Ordinal:IA
fr-CAFrench (Canada)
Virus varicelle-zona , IgM:Présence-Seuil:Temps ponctuel:LCR:Ordinal:IA
fr-FRFrench (France)
Varicelle zona virus Ac IgM:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoanalyse
el-GRGreek (Greece)
Ιός ανεμευλογιάς-έρπητα ζωστήρα IgM ανοσοσφαιρίνη:PrThr:Χρονική στιγμή:ΕΝΥ:Τακτική:IA
it-ITItalian (Italy)
Varicella zoster, virus Ab.IgM:PrThr:Pt:LCS:Ord:IA
pt-BRPortuguese (Brazil)
Varicella zoster vírus Ac.IgM:Limiar:Pt:LCR:Ord:Imunoensaio
ru-RURussian (Russian Federation)
Varicella zoster вирус Ат.IgM:PrThr:ТчкВрм:ЦСЖ:Пор:IA
es-MXSpanish (Mexico)
Ab.IgM del virus de la varicela zóster:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunoensayo
es-ESSpanish (Spain)
Virus Varicella zoster IgM:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:IA
tr-TRTurkish (Turkey)
Varicella zoster virüsü Ab.IgM:MevcEşik:Zmlı:BOS:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=69930-6