Version 2.73

70666-3Cold agglutinin [Presence] in Serum by 22 degree C incubationActive

Term Description

Cold agglutinins are usually determined at refrigerator temperatures (4 degrees C). In positive cases, surgeons may request testing at additional temperatures, including 18 degrees C, room temperature (22 degrees C), and 28 degrees C, to determine how cold the patient's body temperature can be dropped during surgery. In cardiovascular surgery, the heart is cooled to 25°C to slow down metabolic processes. Since the blood of patients with a history of cold antibodies or cold hemagglutinin disease (such as Raynaud's) is likely to contain cold antibodies, such as anti-M, anti-I and anti-I, testing at various temperatures is performed in order to prevent an acute hemolytic episode.
Source: Regenstrief LOINC

Part Descriptions

LP16679-0   Cold agglutinin
A cold agglutinin is an autoimmune disease in which the body produces antibodies against red blood cells, causing the cells to agglutinate (clump together). These antibodies are usually IgM. The primary form of cold agglutinin disease is idiopathic. In other cases, the disease is a result of an underlying condition. Cold aggulitinin disease is known to occur in adults with a lymphoproliferative disease, such as lymphoma and chronic lymphoid leukemia, and in children with infections such as Mycoplasma pneumonia, mononucleosis, and HIV. Cold agglutinins affect many blood tests, such as red blood cell count, and by default, the mean corpuscular hemoglobin and mean corpuscular volume. If these indices are very high, a technologist should suspect a cold agglutinin. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Cold agglutinin (Wikipedia)

LP16679-0   Cold agglutinin
Red cell antibodies that react more strongly at temperatures below 37 deg C. Source: Regenstrief Institute

Fully-Specified Name

Cold agglutinin
22 deg C incubation

Additional Names

Short Name
CA Ser Ql 22 deg C inc
Display Name
Cold agglutinin 22 degree C incubation Ql (S)
Consumer Name Alpha
Cold Agglutinin, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.40
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
koude agglutinatie:aanwezigheid:moment:serum:ordinaal:22 graden C-incubatie
fr-CAFrench (Canada)
Agglutinine froide:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Incubation @ 22 C
fr-FRFrench (France)
Agglutinines froides:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Incubation à 22°C
it-ITItalian (Italy)
Agglutinina a freddo:PrThr:Pt:Siero:Ord:22° C, incubazione
pt-BRPortuguese (Brazil)
Crio-aglutininas::Pt:Soro:Ord:22 deg C incubação
es-MXSpanish (Mexico)
Aglutinina fría:Presencia o umbral:Punto temporal:Suero:Ordinal:Incubación a 22 grados C
es-ESSpanish (Spain)
Crioaglutininas:PrThr:Punto temporal:Suero:Ord:22 ºC de incubación
tr-TRTurkish (Turkey)
Soğuk aglutinin:MevcEşik:Zmlı:Ser:Srl:22 C derc inkübasyon

LOINC FHIR® API Example - CodeSystem Request Get Info