LOINC
Version 2.73

71783-5Yellow fever virus neutralizing antibody [Titer] in Cerebral spinal fluid by Neutralization testActive

Term Description

Vaccination associated encephalitis is possible. CNS infection due to wild Yellow Fever virus would be rare.
Source: Regenstrief LOINC

Part Descriptions

LP17143-6   Yellow fever virus
Yellow fever (also called yellow jack, black vomit or vomito negro in Spanish, or sometimes American Plague) is an acute viral disease. It is an important cause of hemorrhagic illness in many African and South American countries despite existence of an effective vaccine. The yellow in the disease name refers to the jaundice that affects some patients. Yellow fever has been a source of several devastating epidemics. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Yellow fever virus (Wikipedia)

LP17143-6   Yellow fever virus
The type species of the Flavivirus genus. Principal vector transmission to humans is by Aedes spp. Mosquitoes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: National Library of Medicine, MeSH 2006, Yellow fever virus (Wikipedia)

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. [PMID:32170698] This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. [PMID:169804] Source: Regenstrief LOINC

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

Fully-Specified Name

Component
Yellow fever virus Ab.Neut
Property
Titr
Time
Pt
System
CSF
Scale
Qn
Method
Neut

Additional Names

Short Name
YFV NAb Titr CSF Nt
Display Name
Yellow fever virus neut ab Neut test (CSF) [Titer]
Consumer Name Alpha
Yellow Fever virus neutralizing antibody, Spinal fluid

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.72
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both

Member of these Groups

LG32769-8 Yellow fever virus

Language Variants Get Info

zh-CNChinese (China)
黄热病病毒 抗体.中和:滴定度:时间点:脑脊液:定量型:中和试验
nl-NLDutch (Netherlands)
gelekoortsvirus As.neutraliserend:titer:moment:liquor cerebrospinalis:kwantitatief:neutralisatietest
fr-CAFrench (Canada)
Virus de la fièvre jaune Ac.neut:Titre:Temps ponctuel:LCR:Quantitatif:Test de neutralisation
fr-FRFrench (France)
Fièvre jaune virus Ac:Titre:Ponctuel:Liquide céphalorachidien:Numérique:Neutralisation
de-DEGerman (Germany)
Gelbfieber-Virus Ak.neutralisierend:Titer:Zeitpunkt:Zerebrospinalflüssigkeit:Quantitativ:Neutralisationstest
it-ITItalian (Italy)
Febbre gialla, virus Ab.Neut:Titr:Pt:LCS:Qn:Neut
pt-BRPortuguese (Brazil)
Febre amarela vírus Ac::Pt:LCR:Qn:
es-MXSpanish (Mexico)
Ab virus de la fiebre amarilla:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Prueba de neutralización
es-ESSpanish (Spain)
Virus de la fiebre amarilla Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Qn:Prueba de neutralización

Example Units

Unit Source
{titer} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=71783-5