Version 2.73

72328-8HLA-A+B+C (class I) IgG Ab [Presence] in Serum by Flow cytometry (FC)Active

Term Description

IgG antibodies to HLA class I antigens (A, B, and C) can be detected by flow cytometry in serum of pre and post-transplant organ recipients. A positive result is an indication of a sensitization to HLA antigens. This code is based on, but not exclusive to, the submitter's test kit, One Lambda's FlowPRA Screening Test, which uses beads coated with common and rare purified HLA Class I or II antigens.
Source: Regenstrief LOINC

Part Description

LP156720-7   HLA-A+B+C Ab.IgG
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.

Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, HLA (Wikipedia)

Fully-Specified Name

Flow cytometry

Additional Names

Short Name
Display Name
HLA-A+B+C (class I) IgG FC Ql (S)
Consumer Name Alpha
HLA-A+B+C (class I) IgG antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.42
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Member of these Panels

LOINC Long Common Name
94428-0 HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC)
94446-2 HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC)
72905-3 Neutrophil Ab and HLA Ab screen panel - Serum or Plasma

Language Variants Get Info

zh-CNChinese (China)
HLA-A+B+C 抗体.IgG:存在情况或阈值:时间点:血清:序数型:流式细胞测量术
nl-NLDutch (Netherlands)
HLA-A+B+C As.IgG:aanwezigheid:moment:serum:ordinaal:flowcytometrie
et-EEEstonian (Estonia)
HLA-A+B+C antikehad.IgG:PrThr:Pt:S:Ord:Voolutsütomeetria
fr-BEFrench (Belgium)
HLA-A+B+C Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal:Cytométrie de flux
fr-CAFrench (Canada)
HLA-A+B+C , IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Cytométrie de flux
fr-FRFrench (France)
HLA-A+B+C anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Cytométrie de flux
it-ITItalian (Italy)
HLA-A+B+C Ab.IgG:PrThr:Pt:Siero:Ord:Citometria a flusso
pt-BRPortuguese (Brazil)
HLA-A+B+C Ac.IgG:Limiar:Pt:Soro:Ord:Citometria de fluxo
ru-RURussian (Russian Federation)
HLA-A+B+C Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:Проточная цитометрия
es-MXSpanish (Mexico)
HLA-A + B + C Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Citometría de flujo (FC)
es-ESSpanish (Spain)
HLA-A+B+C IgG:PrThr:Punto temporal:Suero:Ord:Citometria de flujo (FC)
tr-TRTurkish (Turkey)
HLA-A+B+C Ab.IgG:MevcEşik:Zmlı:Ser:Srl:Akış sitometri

LOINC FHIR® API Example - CodeSystem Request Get Info