Version 2.77

Part Descriptions

LP14981-2   ALPRAZolam
Alprazolam (brand name Xanax) is a short-acting anxiolytic of the benzodiazepine class of psychoactive drugs, used to treat anxiety and panic disorders. It works by binding to gamma aminobutyric acid (GABA) receptors in the brain to increase GABA-mediated synaptic inhibition. Alprazolam is also sometimes used to treat depression, fear of open spaces (agoraphobia), and premenstrual syndrome. Alprazolam can be habit-forming and some of the more serious potential side effects are: shortness of breath, seizures, hallucinating, severe skin rash, yellowing of the skin or eyes, depression, memory problems, confusion, problems with speech, unusual changes in behavior or mood, and suicidal thoughts. Source: Regenstrief LOINC, MedlinePlus: a684001

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

Fully-Specified Name

Component
ALPRAZolam
Property
MCnc
Time
Pt
System
Saliva
Scale
Qn
Method

Additional Names

Short Name
Alpraz Sal-mCnc
Display Name
ALPRAZolam (Sal) [Mass/Vol]
Consumer Name Alpha Get Info
ALPRAZolam, Saliva

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
8447

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Alprazolam:Concentración de masa:Punto temporal:Saliva:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) ALPRAZolam:Concentración de masa:Punto temporal:Saliva:Cuantitativo:
et-EE Estonian (Estonia) Alprasolaam:MCnc:Pt:Sal:Qn:
Synonyms: Juhuslik Kvantitatiivne Sülg
fr-CA French (Canada) Aprazolam:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:
fr-FR French (France) Alprazolam:Masse/Volume:Ponctuel:Salive:Numérique:
fr-BE French (Belgium) Alprazolam:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:
it-IT Italian (Italy) Alprazolam:MCnc:Pt:Saliva:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) alprazolam:massa/volume:moment:speeksel:kwantitatief:
pt-BR Portuguese (Brazil) Alprazolam::Pt:Saliva:Qn:
ru-RU Russian (Russian Federation) Алпразолам:МассКонц:ТчкВрм:Слюна:Колич:
Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Alprazolam:KütlKons:Zmlı:Tükürük:Kant:
zh-CN Chinese (China) 阿普唑仑:质量浓度:时间点:唾液:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 津;津液;涎 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72381-7