72755-2
clonazePAM [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Active
Part Descriptions
LP16086-8 clonazePAM
Clonazepam is a powerful benzodiazepine that was originally prescribed to treat seizure disorders but has increasingly been used to treat mood disorders including panic disorder and depression. Clonazepam has been used to accelerate the response of selective serotonin reuptake inhibitors (SSRIs) fluoxetine, fluvoxamine and sertraline and for treatment-resistant and prolonged depression. Extended use of clonazepam with SSRIs helps prevent the recurrence of depression. Clonazepam more effectively treats unipolar than bipolar depression. Its mode of action is believed to be associated with the gamma-aminobutyric acid (GABA) system. PMID: 19330803
Source: Regenstrief LOINC
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- clonazePAM
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- clonazePAM Sal Cfm-mCnc
- Display Name
- clonazePAM Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- clonazePAM, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6289
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Clonazepam: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | clonazePAM: |
et-EE | Estonian (Estonia) | Klonasepaam: Synonyms: Juhuslik Kvantitatiivne Sülg |
fr-CA | French (Canada) | Clonazépam: |
fr-FR | French (France) | Clonazépam: |
fr-BE | French (Belgium) | Clonazépam: |
it-IT | Italian (Italy) | Clonazepam: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | clonazepam: |
pt-BR | Portuguese (Brazil) | Clonazepam: |
ru-RU | Russian (Russian Federation) | Клоназепам: Synonyms: Количественный Массовая концентрация Точка во времени; |
tr-TR | Turkish (Turkey) | Klonazepam: Synonyms: Teyid |
zh-CN | Chinese (China) | 氯硝安定: Synonyms: 可用数量表示的; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
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