LOINC
Version 2.67

72966-5quiNIDine induced neutrophil IgG Ab [Presence] in Serum or Plasma by Flow cytometry (FC)Active

Part Descriptions

LP16271-6   quiNIDine
Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent in the heart. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree. Chemically it is known as (2-ethenyl-4-azabicyclo[2.2.2]oct-5-yl)- (6-methoxyquinolin-4-yl)-methanol OR 6'-mehoxycinchonan-9-ol OR 6' methoxy-alpha (5-vinyl-2-quinuclidinyl)-4-quinoline methanol. Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (INa). Quinidine's effect on INa is known as a use dependent block. This means that at higher heart rates, the block increases, while at lower heart rates the block decreases. The effect of blocking the fast inward sodium current causes the phase 0 depolarization of the cardiac action potential to decrease (decreased Vmax). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Quinidine (Wikipedia)

LP16271-6   quiNIDine
An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
quiNIDine induced neutrophil Ab.IgG
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
Flow cytometry

Additional Names

Short Name
quiNIDine (neut) IgG SerPl Ql FC
Display Name
quiNIDine induced neutrophil IgG FC Ql

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
72909-5 Drug induced neutrophil Ab panel - Serum or Plasma

Language Variants Get Info

zh-CNChinese (CHINA)
奎尼丁 诱导型嗜中性粒细胞抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:流式细胞测量术
nl-NLDutch (NETHERLANDS)
quinidine geïnduceerd neutrofiel As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:flowcytometrie
fr-FRFrench (FRANCE)
Polynucléaires neutrophiles anticorps IgG induits par quinidine:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Cytométrie de flux
it-ITItalian (ITALY)
Chinidina , Ab.IgG neutrofili indotti da:PrThr:Pt:Siero/Plasma:Ord:Citometria a flusso
pt-BRPortuguese (BRAZIL)
ru-RURussian (RUSSIAN FEDERATION)
Хинидин индуцированный нейтрофил Ат.IgG:PrThr:ТчкВрм:Сыв/Плаз:Пор:Проточная цитометрия
es-ESSpanish (SPAIN)
Quinidina Acs. IgG neutrófilos inducidos:PrThr:Punto temporal:Suero o Plasma:Ord:Citometria de flujo (FC)
tr-TRTurkish (TURKEY)
Kuinidin uyarılmış nötrofil Ab.IgG:MevcEşik:Zmlı:Ser/Plaz:Srl:Akış sitometri

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72966-5